CD106 / VCAM1 (1.4C3), 0.2mg/mL

About this product

CD106 (also known as vascular cell adhesion molecule-1, or VCAM-1) is a member of the Ig superfamily of adhesion molecules. It is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte beta-1 integrin VLA-4 and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNUB0149-500

Size / count

1x 500 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

CD106; VCAM-1; Vascular Cell Adhesion Molecule 1; VCAM1; INCAM-100

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

VCAM1

Gene ID

7412

NCBI Gene ID

109225

UniProt

P19320

Swiss Prot

P19320

Host

Mouse

Species Reactivity

Human

Reactivity

CD106|VCAM-1

Immunogen

Stimulated human umbilical vein endothelial cells (HUVEC)

Target Antigen

CD106 | VCAM-1

Clonality

Monoclonal

Clone

1.4C3

Type

Primary

Source

Animal

Origin

Animal

Applications

Flow (published) |IHC, FFPE (verified) |IP (published) |WB (published)

Field of Research

Immunology

Positive Control

Human placenta or tonsil

Stability

2 years

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

~110 kDa

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. J Virol (1997) 71(11): 8522-8530. (WB) J Immunol (1999) 162: 2990-2996. (IP; WB) Cardiovasc Res (2007) 76(3): 494-505. (Flow, surface; cell-based ELISA)

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)

Conjugate

Purified, with BSA