CD106 / VCAM1 (1.4C3), 1mg/mL

Catalog number BNUM0149-50

Price for BNUM0149-50

Size / count 1x 50 µL

About this product

CD106 (also known as vascular cell adhesion molecule-1, or VCAM-1) is a member of the Ig superfamily of adhesion molecules. It is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte beta-1 integrin VLA-4 and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUM0149-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD106; VCAM-1; Vascular Cell Adhesion Molecule 1; VCAM1; INCAM-100
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: VCAM1
Gene ID: 7412
NCBI Gene ID: 109225
UniProt: P19320
Swiss Prot: P19320
Host: Mouse
Species Reactivity: Human
Reactivity: CD106|VCAM-1
Immunogen: Stimulated human umbilical vein endothelial cells (HUVEC)
Target Antigen: CD106 | VCAM-1
Clonality: Monoclonal
Clone: 1.4C3
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow (published) |IHC, FFPE (verified) |IP (published) |WB (published)
Field of Research: Immunology
Positive Control: Human placenta or tonsil
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: ~110 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. J Virol (1997) 71(11): 8522-8530. (WB) J Immunol (1999) 162: 2990-2996. (IP; WB) Cardiovasc Res (2007) 76(3): 494-505. (Flow, surface; cell-based ELISA)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Product documents

Supporting information for this product.

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