CD117 (C117/370), 1mg/mL

Catalog number BNUM0370-50

Price for BNUM0370-50

Size / count 1x 50 µL

About this product

CD117, also known as c-kit, is a member if the immunoglobin superfamily. It is a receptor tyrosine kinase that is expressed on hematopoietic progenitor cells. It binds to the c-kit ligand KITLG/SCF and has roles in cell survival and cell proliferation. Upon ligand binding, it activates a number of signaling pathways. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUM0370-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD117; c-Kit; p145; Mast/stem Cell Growth Factor Receptor
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: KIT
Gene ID: 3815
NCBI Gene ID: 479754
UniProt: P10721
Swiss Prot: P10721
Host: Mouse
Species Reactivity: Human
Reactivity: CD117
Immunogen: Recombinant human CD117 protein
Target Antigen: CD117
Clonality: Monoclonal
Clone: C117/370
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Signal transduction
Positive Control: Gastrointestinal Stromal Tumor (GIST) or testicular germ cell tumor. Melanocytes in the basal layer of the epidermis and mast cells in the dermis of normal skin.
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: 145 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for CD117 (C117/370), 1mg/mL?

The catalog number for CD117 (C117/370), 1mg/mL is BNUM0370-50.

What sizes are available for CD117 (C117/370), 1mg/mL?

CD117 (C117/370), 1mg/mL is available in the following size(s): 1x 50 µL.

Is CD117 (C117/370), 1mg/mL in stock?

CD117 (C117/370), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD117 (C117/370), 1mg/mL?

CD117 (C117/370), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD117 (C117/370), 1mg/mL?

Estimated delivery time for CD117 (C117/370), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD117 (C117/370), 1mg/mL?

The safety data sheet for CD117 (C117/370), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD117 (C117/370), 1mg/mL used for?

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.