CD117 (C117/370), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0370-500

Price for BNCB0370-500

Size / count 1x 500 µL

About this product

CD117, also known as c-kit, is a member if the immunoglobin superfamily. It is a receptor tyrosine kinase that is expressed on hematopoietic progenitor cells. It binds to the c-kit ligand KITLG/SCF and has roles in cell survival and cell proliferation. Upon ligand binding, it activates a number of signaling pathways. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB0370-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD117; c-Kit; p145; Mast/stem Cell Growth Factor Receptor
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: KIT
Gene ID: 3815
NCBI Gene ID: 479754
UniProt: P10721
Swiss Prot: P10721
Host: Mouse
Species Reactivity: Human
Reactivity: CD117
Immunogen: Recombinant human CD117 protein
Target Antigen: CD117
Clonality: Monoclonal
Clone: C117/370
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Signal transduction
Positive Control: Gastrointestinal Stromal Tumor (GIST) or testicular germ cell tumor. Melanocytes in the basal layer of the epidermis and mast cells in the dermis of normal skin.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 145 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for CD117 (C117/370), Biotin conjugate, 0.1mg/mL?

The catalog number for CD117 (C117/370), Biotin conjugate, 0.1mg/mL is BNCB0370-500.

What sizes are available for CD117 (C117/370), Biotin conjugate, 0.1mg/mL?

CD117 (C117/370), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD117 (C117/370), Biotin conjugate, 0.1mg/mL in stock?

CD117 (C117/370), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD117 (C117/370), Biotin conjugate, 0.1mg/mL?

CD117 (C117/370), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD117 (C117/370), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for CD117 (C117/370), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD117 (C117/370), Biotin conjugate, 0.1mg/mL?

The safety data sheet for CD117 (C117/370), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD117 (C117/370), Biotin conjugate, 0.1mg/mL used for?

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.