CD117 (C117/370), CF594 conjugate, 0.1mg/mL

Catalog number BNC940370-100

Price for BNC940370-100

Size / count 1x 100 µL

About this product

CD117, also known as c-kit, is a member if the immunoglobin superfamily. It is a receptor tyrosine kinase that is expressed on hematopoietic progenitor cells. It binds to the c-kit ligand KITLG/SCF and has roles in cell survival and cell proliferation. Upon ligand binding, it activates a number of signaling pathways. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC940370-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD117; c-Kit; p145; Mast/stem Cell Growth Factor Receptor
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: KIT
Gene ID: 3815
NCBI Gene ID: 479754
UniProt: P10721
Swiss Prot: P10721
Host: Mouse
Species Reactivity: Human
Reactivity: CD117
Immunogen: Recombinant human CD117 protein
Target Antigen: CD117
Clonality: Monoclonal
Clone: C117/370
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Signal transduction
Positive Control: Gastrointestinal Stromal Tumor (GIST) or testicular germ cell tumor. Melanocytes in the basal layer of the epidermis and mast cells in the dermis of normal skin.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 145 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for CD117 (C117/370), CF594 conjugate, 0.1mg/mL?

The catalog number for CD117 (C117/370), CF594 conjugate, 0.1mg/mL is BNC940370-100.

What sizes are available for CD117 (C117/370), CF594 conjugate, 0.1mg/mL?

CD117 (C117/370), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD117 (C117/370), CF594 conjugate, 0.1mg/mL in stock?

CD117 (C117/370), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD117 (C117/370), CF594 conjugate, 0.1mg/mL?

CD117 (C117/370), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD117 (C117/370), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for CD117 (C117/370), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD117 (C117/370), CF594 conjugate, 0.1mg/mL?

The safety data sheet for CD117 (C117/370), CF594 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102639/msds/bnc940370-100.pdf.

What is CD117 (C117/370), CF594 conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.