Tyrosinase (Melanoma Marker) (TYR/2024R), CF740 conjugate, 0.1mg/mL — image 1 of 2

Product details

Tyrosinase (Melanoma Marker) (TYR/2024R), CF740 conjugate, 0.1mg/mL

Catalog number BNC742024-500

Price for BNC742024-500

Size / count 1x 500 µL

About this product

This antibody recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC742024-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ATN, CMM8, LB24-AB, Monophenol monooxygenase, OCA1, OCA1A, Oculocutaneous albinism IA, SHEP3, SK29-AB, Tumor rejection antigen AB, TYR
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TYR
Gene ID: 7299
NCBI Gene ID: 503555
UniProt: P14679
Swiss Prot: P14679
Host: Rabbit
Species Reactivity: Human
Reactivity: Tyrosinase
Immunogen: Recombinant full-length human tyrosinase (TYR) protein
Target Antigen: Tyrosinase
Clonality: Recombinant Monoclonal
Clone: TYR/2024R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer
Positive Control: SK-MEL-19, SK-MEL-30 cells or Melanoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 70-80 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for Tyrosinase (Melanoma Marker) (TYR/2024R), CF740 conjugate, 0.1mg/mL?

The catalog number for Tyrosinase (Melanoma Marker) (TYR/2024R), CF740 conjugate, 0.1mg/mL is BNC742024-500.

What sizes are available for Tyrosinase (Melanoma Marker) (TYR/2024R), CF740 conjugate, 0.1mg/mL?

Tyrosinase (Melanoma Marker) (TYR/2024R), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Tyrosinase (Melanoma Marker) (TYR/2024R), CF740 conjugate, 0.1mg/mL in stock?

Tyrosinase (Melanoma Marker) (TYR/2024R), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Tyrosinase (Melanoma Marker) (TYR/2024R), CF740 conjugate, 0.1mg/mL?

Tyrosinase (Melanoma Marker) (TYR/2024R), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Tyrosinase (Melanoma Marker) (TYR/2024R), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Tyrosinase (Melanoma Marker) (TYR/2024R), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Tyrosinase (Melanoma Marker) (TYR/2024R), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Tyrosinase (Melanoma Marker) (TYR/2024R), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0299061270361e101137/msds/bnc742024-500.pdf.

What is Tyrosinase (Melanoma Marker) (TYR/2024R), CF740 conjugate, 0.1mg/mL used for?

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.