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Product details

CD11c (HC1/1), 0.2mg/mL

Catalog number BNUB0152-500

Price for BNUB0152-500

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Size / count 1x 500 µL

About this product

CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells. It induces cellular activation and helps trigger neutrophil respiratory burst. It is expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB0152-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD11 antigen-like family member B|CD11b/CD18|CD49d|Cell surface glycoprotein MAC-1 subunit alpha|Complement Component Receptor 3 Alpha|CR3 Alpha Chain (CR3A) |Integrin alpha-M|Integrin beta 2 alpha subunit|ITGAM|Leukocyte adhesion receptor MO1; Ly-40|Mac-1a|MAC1|Mac1, alpha subunit|MAC1A|Macrophage antigen alpha polypeptide; MO1A|Neutrophil adherence receptor alpha M subunit
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ITGAX
Gene ID
3687
NCBI Gene ID
248472
UniProt
P20702
Swiss Prot
P20702
Host
Mouse
Species Reactivity
Human
Reactivity
CD11c
Immunogen
Human monocytic U937 phorbol ester-treated cells
Target Antigen
CD11c
Clonality
Monoclonal
Clone
HC1/1
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |Flow, surface (published) |Functional studies (published) |IP (published)
Field of Research
Cell adhesion, Immunology
Positive Control
Human dendritic cells. Human lymph nodes and tonsils.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
145 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. Hybridoma (1988) 7:2, 167-176. (IHC) J Exp Med (1991) 174 (6): 1313-1322. (Flow; receptor activation; IP)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for CD11c (HC1/1), 0.2mg/mL?

The catalog number for CD11c (HC1/1), 0.2mg/mL is BNUB0152-500.

What sizes are available for CD11c (HC1/1), 0.2mg/mL?

CD11c (HC1/1), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is CD11c (HC1/1), 0.2mg/mL in stock?

CD11c (HC1/1), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD11c (HC1/1), 0.2mg/mL?

CD11c (HC1/1), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD11c (HC1/1), 0.2mg/mL?

Estimated delivery time for CD11c (HC1/1), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD11c (HC1/1), 0.2mg/mL?

The safety data sheet for CD11c (HC1/1), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD11c (HC1/1), 0.2mg/mL used for?

CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells. It induces cellular activation and helps trigger neutro

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

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