Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), CF740 conjugate, 0.1mg/mL

Catalog number BNC741951-500

Price for BNC741951-500

Size / count 1x 500 µL

About this product

Bcl-6 is a transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. It forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Bcl-6 allows GC B-cells to proliferate very rapidly in response to T-cell dependent antigens and tolerate the physiological DNA breaks required for immunglobulin class switch recombination and somatic hypermutation without inducing a p53/TP53-dependent apoptotic response. Antibodies to Bcl-6 are helpful in a number of diagnostic settings, for example in the differential diagnosis of small B-cell lymphoma, and in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) .Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC741951-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Bcl-6; B-Cell Lymphoma 6 Protein; B-cell lymphoma 5 protein; Zinc Finger Protein 51; zinc finger transcription factor BCL6S; BCL6 Transcription Repressor
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: BCL6
Gene ID: 604
NCBI Gene ID: 478588
UniProt: P41182
Swiss Prot: P41182
Host: Rabbit
Species Reactivity: Human
Reactivity: Bcl-6
Immunogen: Recombinant human bcl-6 protein fragment (around aa 256-389) (Exact sequence is proprietary)
Target Antigen: Bcl-6
Clonality: Monoclonal
Clone: BCL6/1951R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Apoptosis, Cancer, Immunology, Transcription factor
Positive Control: Raji or Ramos cells. Tonsil
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 95 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), CF740 conjugate, 0.1mg/mL?

The catalog number for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), CF740 conjugate, 0.1mg/mL is BNC741951-500.

What sizes are available for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), CF740 conjugate, 0.1mg/mL?

Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), CF740 conjugate, 0.1mg/mL in stock?

Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), CF740 conjugate, 0.1mg/mL?

Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a5061270361e10570d/msds/bnc741951-500.pdf.

What is Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), CF740 conjugate, 0.1mg/mL used for?

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.