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Product details
Catalog number BNC742089-100
Price for BNC742089-100
Size / count 1x 100 µL
Cu-Zn superoxide dismutase-1 (SOD-1) is a well-characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically, SOD-1 facilitates the dismutation of oxygen radicals to hydrogen peroxide and also catalyzes pro-oxidant reactions, which include the peroxidase activity and hydroxyl radical generating activity. SOD-1 is ubiquitously expressed in somatic cells and functions as a homodimer. Defects in the gene encoding SOD-1 have been implicated in the progression of neurological diseases, including amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by the loss of spinal motor neurons, Down syndrome and Alzheimer s disease. In familial ALS, several mutations in SOD-1 predominate, resulting in the loss of zinc binding, the loss of scavenging activity of SOD-1, and correlate with an increase in neurotoxicity and motor neuron death.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF740 conjugate, 0.1mg/mL is BNC742089-100.
Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a9061270361e1070cd/msds/bnc742089-100.pdf.
Cu-Zn superoxide dismutase-1 (SOD-1) is a well-characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically, SOD-1 facilitates the dismutation of oxygen radicals to hydrogen peroxide and also catalyzes pro-oxidant
Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.
Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.
Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.
