CD16 (C16/1045), CF594 conjugate, 0.1mg/mL

Catalog number BNC941045-500

Price for BNC941045-500

Size / count 1x 500 µL

About this product

This antibody recognizes CD16 (FcÎ3RIII), the low-affinity receptor for IgG with an apparent molecular weight of 50-80 kDa. Two similar genes represent CD16, CD16A (FcÎ3RIIIA), which exists as a hetero-oligomeric polypeptide-anchored form in macrophages and NK cells and CD16B (FcÎ3RIIIB), which exist as a monomeric GPI-anchored form in neutrophils. Furthermore, there are two known polymorphisms of CD16B, NA-1 and NA-2. Individuals homozygous for NA-2 show a lower phagocytic capacity compared with NA-1. CD16 binds IgG in the form of immune complexes and shows preferential binding of IgG1 and IgG3 isotypes and minimal binding of IgG2 and IgG4. Upon IgG binding, both CD16 isoforms initiate signal transduction cascades that lead to a variety of responses including antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, degranulation and proliferation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC941045-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD162; CLA; Cutaneous lymphocyte associated antigen; P-selectin glycoprotein ligand 1; PSGL1; Selectin P ligand; SELPLG
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: FCGR3A
Gene ID: 2214
NCBI Gene ID: 372679
UniProt: P08637
Swiss Prot: P08637
Host: Mouse
Species Reactivity: Human
Reactivity: CD16|Fc gamma receptor III
Immunogen: Recombinant human CD16 protein
Target Antigen: CD16 | Fc gamma receptor III
Clonality: Monoclonal
Clone: C16/1045
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, surface (verified) |IF (verified)
Field of Research: Immunology
Positive Control: K-562 or U-937 cells. Lymph nodes and tonsils.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 50-80 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. Knapp W. et al. (eds) Leukocyte Typing IV, Oxford University Press, Oxford, 1989.
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for CD16 (C16/1045), CF594 conjugate, 0.1mg/mL?

The catalog number for CD16 (C16/1045), CF594 conjugate, 0.1mg/mL is BNC941045-500.

What sizes are available for CD16 (C16/1045), CF594 conjugate, 0.1mg/mL?

CD16 (C16/1045), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD16 (C16/1045), CF594 conjugate, 0.1mg/mL in stock?

CD16 (C16/1045), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD16 (C16/1045), CF594 conjugate, 0.1mg/mL?

CD16 (C16/1045), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD16 (C16/1045), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for CD16 (C16/1045), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD16 (C16/1045), CF594 conjugate, 0.1mg/mL?

The safety data sheet for CD16 (C16/1045), CF594 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0299061270361e10102d/msds/bnc941045-500.pdf.

What is CD16 (C16/1045), CF594 conjugate, 0.1mg/mL used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.