CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), 1mg/mL

Catalog number BNUM0679-50

Price for BNUM0679-50

Size / count 1x 50 µL

About this product

Recognizes a cell surface protein of 220-240 kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius) ; 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs) ; and 3) SPG1 (spastic paraplegia) . The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUM0679-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CAML1, HSAS1, Hyd, L1 Cell Adhesion Molecule, L1-NCAM, MASA, MIC5, NCAM-L1, Nerve-growth factor-inducible large external glycoprotein, Neural cell adhesion molecule L1, NILE, S10, SPG1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: L1CAM
Gene ID: 3897
NCBI Gene ID: 52818
UniProt: P32004
Swiss Prot: P32004
Host: Mouse
Species Reactivity: Human
Reactivity: CD171|L1CAM
Immunogen: Homogenous suspension of 16 week human fetal brain
Target Antigen: CD171 | L1CAM
Clonality: Monoclonal
Clone: UJ127
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, surface (published) |IHC, FFPE (published) |IP (published) |WB (published)
Field of Research: Cancer, Cell adhesion, Developmental biology
Positive Control: Neuroblastomas or Schwannomas
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: 220-240 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. Eur J Gynaecol Oncol (2008) 29(1):26-30. (IHC, FFPE; WB) Anticancer Res (2009) 29: 1195-1200. (IHC, FFPE) Mol Biol Cell (2010) 21: 1671-1685. (IHC, FFPE; Flow, IP)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), 1mg/mL?

The catalog number for CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), 1mg/mL is BNUM0679-50.

What sizes are available for CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), 1mg/mL?

CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), 1mg/mL is available in the following size(s): 1x 50 µL.

Is CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), 1mg/mL in stock?

CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), 1mg/mL?

CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), 1mg/mL?

Estimated delivery time for CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), 1mg/mL?

The safety data sheet for CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), 1mg/mL used for?

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.