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Product details

CD1a (C1A/711), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0711-500

Price for BNCB0711-500

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Size / count 1x 500 µL

About this product

At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa) . Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB0711-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Cortical thymocyte antigen CD1A, Epidermal dendritic cell marker CD1a antibody, FCB6, HTA1, T cell surface antigen T6 / Leu 6, T-Cell Surface Glycoprotein CD1A
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD1A
Gene ID
909
NCBI Gene ID
1309
UniProt
P06126
Swiss Prot
P06126
Host
Mouse
Species Reactivity
Human
Reactivity
CD1a|HTA1
Immunogen
Recombinant human CD1a protein
Target Antigen
CD1a | HTA1
Clonality
Monoclonal
Clone
C1A/711
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer
Positive Control
MOLT-4 cells. Paracortex in a tonsil or a reactive lymph node.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
49 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for CD1a (C1A/711), Biotin conjugate, 0.1mg/mL?

The catalog number for CD1a (C1A/711), Biotin conjugate, 0.1mg/mL is BNCB0711-500.

What sizes are available for CD1a (C1A/711), Biotin conjugate, 0.1mg/mL?

CD1a (C1A/711), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD1a (C1A/711), Biotin conjugate, 0.1mg/mL in stock?

CD1a (C1A/711), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD1a (C1A/711), Biotin conjugate, 0.1mg/mL?

CD1a (C1A/711), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD1a (C1A/711), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for CD1a (C1A/711), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD1a (C1A/711), Biotin conjugate, 0.1mg/mL?

The safety data sheet for CD1a (C1A/711), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD1a (C1A/711), Biotin conjugate, 0.1mg/mL used for?

At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein,

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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