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Product details
Catalog number BNC741898-100
Price for BNC741898-100
Size / count 1x 100 µL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000, full-length human proteins. DNMT3A is required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3 (H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for DNMT3A / DNA Methyltransferase 3 Alpha (PCRP-DNMT3A-1E2), CF740 conjugate, 0.1mg/mL is BNC741898-100.
DNMT3A / DNA Methyltransferase 3 Alpha (PCRP-DNMT3A-1E2), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
DNMT3A / DNA Methyltransferase 3 Alpha (PCRP-DNMT3A-1E2), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
DNMT3A / DNA Methyltransferase 3 Alpha (PCRP-DNMT3A-1E2), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for DNMT3A / DNA Methyltransferase 3 Alpha (PCRP-DNMT3A-1E2), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for DNMT3A / DNA Methyltransferase 3 Alpha (PCRP-DNMT3A-1E2), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b8061270361e10c263/msds/bnc741898-100.pdf.
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000, full-length human proteins. DNMT3A is required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during developm
No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.
Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.
The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.
