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Product details

CD28 (204.12), 0.2mg/mL

Catalog number BNUB0164-500

Price for BNUB0164-500

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Size / count 1x 500 µL

About this product

Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB0164-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
T-cell-specific surface glycoprotein CD28; Tp44
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD28
Gene ID
940
NCBI Gene ID
591629
UniProt
P10747
Swiss Prot
P10747
Host
Mouse
Species Reactivity
Cow, Human, Mouse, Pig, Sheep
Reactivity
CD28
Immunogen
Stimulated human leucocytes
Target Antigen
CD28
Clonality
Monoclonal
Clone
204.12
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |Functional studies (published) |IF (verified)
Field of Research
Immunology
Positive Control
Jurkat cells or human lymph nodes and tonsils.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
44 kDa (monomer) ; 88 kDa (dimer)
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. Clin Exp Immunol (2010) 162: 516-527. (receptor activation)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for CD28 (204.12), 0.2mg/mL?

The catalog number for CD28 (204.12), 0.2mg/mL is BNUB0164-500.

What sizes are available for CD28 (204.12), 0.2mg/mL?

CD28 (204.12), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is CD28 (204.12), 0.2mg/mL in stock?

CD28 (204.12), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD28 (204.12), 0.2mg/mL?

CD28 (204.12), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD28 (204.12), 0.2mg/mL?

Estimated delivery time for CD28 (204.12), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD28 (204.12), 0.2mg/mL?

The safety data sheet for CD28 (204.12), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0298061270361e100a4f/msds/bnub0164-500.pdf.

What is CD28 (204.12), 0.2mg/mL used for?

Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 func

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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