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Product details

CD284 / TLR4 (TLR4/230), CF647 conjugate, 0.1mg/mL

Catalog number BNC470230-500

Price for BNC470230-500

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Size / count 1x 500 µL

About this product

This MAb reacts with human Toll-like receptor 2 (TLR4) . It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC470230-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
ARMD10; CD284; hToll; TLR4; TOLL; Toll Endotoxin Hyporesponsiveness; Toll-like receptor 4
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TLR4
Gene ID
7099
NCBI Gene ID
174312
UniProt
O00206
Swiss Prot
O00206
Host
Mouse
Species Reactivity
Dog, Guinea pig, Human, Monkey, Pig, Rat
Reactivity
CD284|TLR4
Immunogen
Recombinant human TLR4 protein
Target Antigen
CD284 | TLR4
Clonality
Monoclonal
Clone
TLR4/230
Type
Primary
Source
Animal
Origin
Animal
Field of Research
Immunology
Positive Control
HeLa, PC12, human peripheral blood cells. Dendritic cells, macrophage and monocytes in tonsil; placenta and adrenal.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
95-120 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for CD284 / TLR4 (TLR4/230), CF647 conjugate, 0.1mg/mL?

The catalog number for CD284 / TLR4 (TLR4/230), CF647 conjugate, 0.1mg/mL is BNC470230-500.

What sizes are available for CD284 / TLR4 (TLR4/230), CF647 conjugate, 0.1mg/mL?

CD284 / TLR4 (TLR4/230), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD284 / TLR4 (TLR4/230), CF647 conjugate, 0.1mg/mL in stock?

CD284 / TLR4 (TLR4/230), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD284 / TLR4 (TLR4/230), CF647 conjugate, 0.1mg/mL?

CD284 / TLR4 (TLR4/230), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD284 / TLR4 (TLR4/230), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for CD284 / TLR4 (TLR4/230), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD284 / TLR4 (TLR4/230), CF647 conjugate, 0.1mg/mL?

The safety data sheet for CD284 / TLR4 (TLR4/230), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102a21/msds/bnc470230-500.pdf.

What is CD284 / TLR4 (TLR4/230), CF647 conjugate, 0.1mg/mL used for?

This MAb reacts with human Toll-like receptor 2 (TLR4) . It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similariti

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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