CD33 (C33/69), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0069-500

Price for BNCB0069-500

Size / count 1x 500 µL

About this product

Recognizes a 67 kDa glycoprotein, which is identified as CD33. It is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM) -containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB0069-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Gp67; My9; Myeloid cell surface antigen CD33; p67; Sialic acid-binding Ig-like lectin 3 (SIGLEC3)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD33
Gene ID: 945
NCBI Gene ID: 83731
UniProt: P20138
Swiss Prot: P20138
Host: Mouse
Species Reactivity: Human
Reactivity: CD33
Immunogen: Recombinant human CD33 protein
Target Antigen: CD33
Clonality: Monoclonal
Clone: C33/69
Type: Primary
Source: Animal
Origin: Animal
Field of Research: Immunology
Positive Control: Human dendritic and mast cells. Human lymph nodes and tonsils.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 67 kDa
References & Citations: Favaloro EJ, Bradstock KF, Kabral A, Grimsley P, Berndt MC: Characterization of monoclonal antibodies to the human myeloid-differentiation antigen, 'gp67' (CD-33). Dis Markers. 1987;5(4):215-25. | Favaloro EJ, Bradstock KF, Kabral A, Grimsley P, Zowtyj H, Zola H: Further characterization of human myeloid antigens (gp160,95; gp150; gp67): investigation of epitopic heterogeneity and non-haemopoietic distribution using panels of monoclonal antibodies belonging to CD-11b, CD-13 and CD-33. Br J Haematol. 1988;69(2):163-71
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for CD33 (C33/69), Biotin conjugate, 0.1mg/mL?

The catalog number for CD33 (C33/69), Biotin conjugate, 0.1mg/mL is BNCB0069-500.

What sizes are available for CD33 (C33/69), Biotin conjugate, 0.1mg/mL?

CD33 (C33/69), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD33 (C33/69), Biotin conjugate, 0.1mg/mL in stock?

CD33 (C33/69), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD33 (C33/69), Biotin conjugate, 0.1mg/mL?

CD33 (C33/69), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD33 (C33/69), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for CD33 (C33/69), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD33 (C33/69), Biotin conjugate, 0.1mg/mL?

The safety data sheet for CD33 (C33/69), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029c061270361e102235/msds/bncb0069-500.pdf.

What is CD33 (C33/69), Biotin conjugate, 0.1mg/mL used for?

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.