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Product details

CD34 (QBEnd/10), CF647 conjugate, 0.1mg/mL

Catalog number BNC470640-500

Price for BNC470640-500

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Size / count 1x 500 µL

About this product

This MAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120 kDa, which is identified as CD34. On the basis of differential sensitivity to degradation by specific enzymes, epitopes of monoclonal antibodies to CD34 are classified intothree main categories, class I, class II and class III. It is a class II antibody whose epitope is resistant to neuraminidase but sensitive to glycoprotease and chymopapain.CD34 expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi's sarcoma, but with a lower specificity.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC470640-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Hematopoietic Progenitor Cell Antigen, HPCA1, Mucosialin
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD34
Gene ID
947
NCBI Gene ID
374990
UniProt
P28906
Swiss Prot
P28906
Host
Mouse
Species Reactivity
Cynomolgus, Human, Rhesus macaque
Reactivity
CD34
Immunogen
Detergent solubilized vesicular suspension prepared from human term placenta
Target Antigen
CD34
Clonality
Monoclonal
Clone
QBEnd/10
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IHC, FFPE (verified)
Field of Research
Angiogenesis, Cancer
Positive Control
KG-1 cells, Tonsil, or Angiosarcoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
90-110 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for CD34 (QBEnd/10), CF647 conjugate, 0.1mg/mL?

The catalog number for CD34 (QBEnd/10), CF647 conjugate, 0.1mg/mL is BNC470640-500.

What sizes are available for CD34 (QBEnd/10), CF647 conjugate, 0.1mg/mL?

CD34 (QBEnd/10), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD34 (QBEnd/10), CF647 conjugate, 0.1mg/mL in stock?

CD34 (QBEnd/10), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD34 (QBEnd/10), CF647 conjugate, 0.1mg/mL?

CD34 (QBEnd/10), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD34 (QBEnd/10), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for CD34 (QBEnd/10), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD34 (QBEnd/10), CF647 conjugate, 0.1mg/mL?

The safety data sheet for CD34 (QBEnd/10), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b3061270361e10a643/msds/bnc470640-500.pdf.

What is CD34 (QBEnd/10), CF647 conjugate, 0.1mg/mL used for?

This MAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120 kDa, which is identified as CD34. On the basis of differential sensitivity to degradation by specific enzymes, epitopes of monoclonal antibodies to CD34 are classified intothree main categories, class I, class

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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