CD35 / CR1 (E11), 1mg/mL

Catalog number BNUM0040-50

Price for BNUM0040-50

Size / count 1x 50 µL

About this product

Recognizes a protein of 210-220 kDa, which is identified as the complement receptor 1 (CR1) /CD35. This MAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This MAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21 /CD35 /CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUM0040-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: C3 binding protein, C3b/C4b receptor, C3BR, C4BR, Complement Component (3b/4b) receptor 1 including Knops blood group system, Complement receptor type 1, KN, Knops blood group antigen
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CR1
Gene ID: 1378
NCBI Gene ID: 334019
UniProt: P17927
Swiss Prot: P17927
Host: Mouse
Species Reactivity: Baboon, Cynomolgus, Human, Rhesus macaque
Reactivity: CD35|CR1
Immunogen: Intact human monocytes
Target Antigen: CD35 | CR1
Clonality: Monoclonal
Clone: E11
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, surface (published) |ELISA (published) |IHC, FFPE (verified) |WB (published)
Field of Research: Immunology
Positive Control: Follicular dendritic cells (FDC) in tonsil
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: 210-220 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. J Immunol (1999) 162:7549-7554. (WB) Clin Exp Immunol (2005) 143: 274-280. (ELISA) Int Immunol (2013) 25(1): 25-33. (Flow, surface)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for CD35 / CR1 (E11), 1mg/mL?

The catalog number for CD35 / CR1 (E11), 1mg/mL is BNUM0040-50.

What sizes are available for CD35 / CR1 (E11), 1mg/mL?

CD35 / CR1 (E11), 1mg/mL is available in the following size(s): 1x 50 µL.

Is CD35 / CR1 (E11), 1mg/mL in stock?

CD35 / CR1 (E11), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD35 / CR1 (E11), 1mg/mL?

CD35 / CR1 (E11), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD35 / CR1 (E11), 1mg/mL?

Estimated delivery time for CD35 / CR1 (E11), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD35 / CR1 (E11), 1mg/mL?

The safety data sheet for CD35 / CR1 (E11), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD35 / CR1 (E11), 1mg/mL used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.