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Product details

Thyroglobulin (Thyroidal Cell Marker) (r2H11), CF740 conjugate, 0.1mg/mL

Catalog number BNC742161-100

Price for BNC742161-100

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Size / count 1x 100 µL

About this product

MAb r2H11 reacts with a partially defined epitope of human thyroglobulin. This epitope is different form the epitope recognized by MAb 6E1. Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC742161-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
AITD3; hTG; TDH3; Tg; Tgn
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TG
Gene ID
7038
NCBI Gene ID
654591
UniProt
P01266
Swiss Prot
P01266
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Reactivity
Thyroglobulin
Immunogen
Human thyroid follicular cells
Target Antigen
Thyroglobulin
Clonality
Recombinant Monoclonal
Clone
R2H11
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Thyroid
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
660 kDa (Dimeric Form)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), Bos taurus (bovine)
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for Thyroglobulin (Thyroidal Cell Marker) (r2H11), CF740 conjugate, 0.1mg/mL?

The catalog number for Thyroglobulin (Thyroidal Cell Marker) (r2H11), CF740 conjugate, 0.1mg/mL is BNC742161-100.

What sizes are available for Thyroglobulin (Thyroidal Cell Marker) (r2H11), CF740 conjugate, 0.1mg/mL?

Thyroglobulin (Thyroidal Cell Marker) (r2H11), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Thyroglobulin (Thyroidal Cell Marker) (r2H11), CF740 conjugate, 0.1mg/mL in stock?

Thyroglobulin (Thyroidal Cell Marker) (r2H11), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Thyroglobulin (Thyroidal Cell Marker) (r2H11), CF740 conjugate, 0.1mg/mL?

Thyroglobulin (Thyroidal Cell Marker) (r2H11), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Thyroglobulin (Thyroidal Cell Marker) (r2H11), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Thyroglobulin (Thyroidal Cell Marker) (r2H11), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Thyroglobulin (Thyroidal Cell Marker) (r2H11), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Thyroglobulin (Thyroidal Cell Marker) (r2H11), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02ae061270361e108b94/msds/bnc742161-100.pdf.

What is Thyroglobulin (Thyroidal Cell Marker) (r2H11), CF740 conjugate, 0.1mg/mL used for?

MAb r2H11 reacts with a partially defined epitope of human thyroglobulin. This epitope is different form the epitope recognized by MAb 6E1. Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

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