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Product details

TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF740 conjugate, 0.1mg/mL

Catalog number BNC741944-100

Price for BNC741944-100

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Size / count 1x 100 µL

About this product

TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases -1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 is identical to EPA (erythroid-potentiation activity) . PTH has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart tissues. Studies have demonstrated that TIMP1 is useful as a biomarker for early detection of colorectal cancer, outperforming CEA. Additionally, TIMP1 studies have demonstrated its role in CRC tumorigenesis, as well as observing its overexpression in metastatic lymph nodes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC741944-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Clgi; Collagenase inhibitor; Collagenase inhibitor; Human; EPA; EPO; Erythroid Potentiating Activity; Erythroid-potentiating activity; Fibroblast collagenase inhibitor; FLJ90373; HCI; Human Collagenase Inhibitor; Metalloproteinase inhibitor 1; Metalloproteinase inhibitor 1 precursor; TIMP 1; TIMP; TIMP metallopeptidase inhibitor 1; TIMP-1; TIMP1 protein; Tissue Inhibitor of Metalloproteinase 1; Tissue inhibitor of metalloproteinases 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TIMP1
Gene ID
7076
NCBI Gene ID
522632
UniProt
P01033
Swiss Prot
P01033
Host
Rabbit
Species Reactivity
Human
Reactivity
TIMP1
Immunogen
Recombinant human full-length TIMP1 protein
Target Antigen
TIMP1
Clonality
Recombinant Monoclonal
Clone
TIMP1/1944R
Type
Primary
Source
Animal
Origin
Animal
Positive Control
293 cell extract or rat brain lysate. Human colon carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
23 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), Bos taurus (bovine)
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF740 conjugate, 0.1mg/mL?

The catalog number for TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF740 conjugate, 0.1mg/mL is BNC741944-100.

What sizes are available for TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF740 conjugate, 0.1mg/mL?

TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF740 conjugate, 0.1mg/mL in stock?

TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF740 conjugate, 0.1mg/mL?

TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF740 conjugate, 0.1mg/mL?

The safety data sheet for TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a0061270361e103ecf/msds/bnc741944-100.pdf.

What is TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF740 conjugate, 0.1mg/mL used for?

TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases -1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 is identical to EPA (erythroid-potentiation act

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

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