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Product details

Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF740 conjugate, 0.1mg/mL

Catalog number BNC742190-100

Price for BNC742190-100

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Size / count 1x 100 µL

About this product

Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC742190-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CyaY; d-FXN; FARR; Frataxin mature form; Frataxin (81-210) ; FRDA; Friedreich ataxia protein; Fxn; i-FXN; m56-FXN; m78-FXN; m81-FXN; X25
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
FXN
Gene ID
2395
NCBI Gene ID
20685
UniProt
Q16595
Swiss Prot
Q16595
Host
Mouse
Species Reactivity
Human
Reactivity
Faxin
Immunogen
Recombinant fragment of human Frataxin (FXN) protein (around aa 57-210) (exact sequence is proprietary)
Target Antigen
Faxin
Clonality
Monoclonal
Clone
FXN/2124
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Positive Control
HepG2, Panc-2, HL-60 or HEK293 cells. Pancreas and Liver.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
14 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), Bos taurus (bovine)
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF740 conjugate, 0.1mg/mL?

The catalog number for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF740 conjugate, 0.1mg/mL is BNC742190-100.

What sizes are available for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF740 conjugate, 0.1mg/mL?

Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF740 conjugate, 0.1mg/mL in stock?

Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF740 conjugate, 0.1mg/mL?

Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b2061270361e10a39e/msds/bnc742190-100.pdf.

What is Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF740 conjugate, 0.1mg/mL used for?

Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possi

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

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