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Product details

Human Von Willebrand Factor Recombinant Rabbit Monoclonal Antibody [PSH09-04] - BSA and Azide free (Detector)

Catalog number HA723059

Price for HA723059

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Size / count 100 µL

About this product

Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. A common hemorrhagic disorder due to defects in von Willebrand factor protein and resulting in impaired platelet aggregation. Von Willebrand disease type 1 is characterized by partial quantitative deficiency of circulating von Willebrand factor, that is otherwise structurally and functionally normal. Clinical manifestations are mucocutaneous bleeding, such as epistaxis and menorrhagia, and prolonged bleeding after surgery or trauma. A hemorrhagic disorder due to defects in von Willebrand factor protein and resulting in altered platelet aggregation. Von Willebrand disease type 2 is characterized by qualitative deficiency and functional anomalies of von Willebrand factor. It is divided in different subtypes including 2A, 2B, 2M and 2N (Normandy variant). The mutant VWF protein in types 2A, 2B and 2M are defective in their platelet-dependent function, whereas the mutant protein in type 2N is defective in its ability to bind factor VIII. Clinical manifestations are mucocutaneous bleeding, such as epistaxis and menorrhagia, and prolonged bleeding after surgery or trauma.

Specifications

Catalog number
HA723059
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Coagulation factor VIII antibody Coagulation factor VIII VWF antibody F8VWF antibody Factor VIII related antigen antibody von Willebrand antigen 2 antibody von Willebrand antigen II antibody Von Willebrand disease antibody Von Willebrand factor precursor antibody VWD antibody vWF antibody VWF_HUMAN antibody
Abbreviation
von Willebrand factor vWF F8VWF
Swiss Prot
P04275 Human
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human von Willebrand factor protein aa 764-1263.
Isotype
IgG
Clone
PSH09-04
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
ELISA (Det)
Positive Control
Recombinant human von Willebrand factor protein.
Concentration
1 mg/mL
Dilution
ELISA (Det): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH09-03] to Human Von Willebrand Factor antibody (Capture) (HA723058) and Recombinant Human Von Willebrand Factor protein as the standard. The reference range value is 370-30,000 pg/ml.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4).
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Human Von Willebrand Factor Recombinant Rabbit Monoclonal Antibody [PSH09-04] - BSA and Azide free (Detector)?

The catalog number for Human Von Willebrand Factor Recombinant Rabbit Monoclonal Antibody [PSH09-04] - BSA and Azide free (Detector) is HA723059.

What sizes are available for Human Von Willebrand Factor Recombinant Rabbit Monoclonal Antibody [PSH09-04] - BSA and Azide free (Detector)?

Human Von Willebrand Factor Recombinant Rabbit Monoclonal Antibody [PSH09-04] - BSA and Azide free (Detector) is available in the following size(s): 100 µL.

Is Human Von Willebrand Factor Recombinant Rabbit Monoclonal Antibody [PSH09-04] - BSA and Azide free (Detector) in stock?

Human Von Willebrand Factor Recombinant Rabbit Monoclonal Antibody [PSH09-04] - BSA and Azide free (Detector) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Human Von Willebrand Factor Recombinant Rabbit Monoclonal Antibody [PSH09-04] - BSA and Azide free (Detector) used for?

Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

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