PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF740 conjugate, 0.1mg/mL — image 1 of 7

Product details

PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF740 conjugate, 0.1mg/mL

Catalog number BNC742146-100

Price for BNC742146-100

Size / count 1x 100 µL

About this product

PU.1 is a member of the ETS family of transcription factors and is important for normal B-cell development. It is expressed in the myeloid lineage and in immature as well as mature B-lymphocytes, with the exception of plasma cells. PU.1 is expressed in germinal center B-cells and mantle B-cells. Various lymphomas are also positive for this marker. It is essential during early B-cell differentiation. The absence of PU.1 results in total block of B-cell development at the pre-pro stage. PU.1 plays a key role in normal myeloid differentiation, and regulates the expression of immunoglobulin and other genes that are important for B-cell development. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC742146-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Transcription Factor spi1; 31kDa Transforming Protein; Hematopoietic Transcription Factor PU.1; SFPI1; SPI1; SPIA; Spleen focus forming virus (SFFV) proviral integration oncogene spi1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SPI1
Gene ID: 6688
NCBI Gene ID: 502511
UniProt: P17947
Swiss Prot: P17947
Host: Mouse
Species Reactivity: Human
Reactivity: PU.1
Immunogen: Recombinant fragment (around aa 16-170) of human PU.1 protein (Exact sequence is proprietary)
Target Antigen: PU.1
Clonality: Monoclonal
Clone: PU1/2146
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research: Immunology, Transcription factors
Positive Control: K-562 Cells, THP-1 cells. Lymph Node, Spleen, Hodgkin's Lymphoma, Colon Carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 40 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF740 conjugate, 0.1mg/mL?

The catalog number for PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF740 conjugate, 0.1mg/mL is BNC742146-100.

What sizes are available for PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF740 conjugate, 0.1mg/mL?

PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF740 conjugate, 0.1mg/mL in stock?

PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF740 conjugate, 0.1mg/mL?

PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF740 conjugate, 0.1mg/mL?

The safety data sheet for PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029c061270361e10234d/msds/bnc742146-100.pdf.

What is PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF740 conjugate, 0.1mg/mL used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.