• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

CD46 (197-2B1), 1mg/mL

Catalog number BNUM0931-50

Price for BNUM0931-50

Sign In for Pricing

Size / count 1x 50 µL

About this product

Recognizes a protein of 52 kDa-58 kDa, identified as CD46 (also known as membrane cofactor protein, MCP) . CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria. This MAb can be applied to test complement activation in pseudo-allergic reactions to acetylsalicylic acid and to test for measles virus infection of cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM0931-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
AHUS2; Complement membrane cofactor protein; MCP; Measles virus receptor; Membrane cofactor protein; MIC10; TLX; Trophoblast leucocyte common antigen; Trophoblast lymphocyte cross reactive antigen
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD46
Gene ID
4179
NCBI Gene ID
510402
UniProt
P15529
Swiss Prot
P15529
Host
Mouse
Species Reactivity
Human
Reactivity
CD46
Immunogen
Stimulated human leukocytes
Target Antigen
CD46
Clonality
Monoclonal
Clone
197-2B1
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |Functional studies (published)
Field of Research
Immunology
Positive Control
K562, U937, HL60, HeLa and Jurkat cells, and human lymphocytes. Lymph node and tonsil.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
52-58 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for CD46 (197-2B1), 1mg/mL?

The catalog number for CD46 (197-2B1), 1mg/mL is BNUM0931-50.

What sizes are available for CD46 (197-2B1), 1mg/mL?

CD46 (197-2B1), 1mg/mL is available in the following size(s): 1x 50 µL.

Is CD46 (197-2B1), 1mg/mL in stock?

CD46 (197-2B1), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD46 (197-2B1), 1mg/mL?

CD46 (197-2B1), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD46 (197-2B1), 1mg/mL?

Estimated delivery time for CD46 (197-2B1), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD46 (197-2B1), 1mg/mL?

The safety data sheet for CD46 (197-2B1), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD46 (197-2B1), 1mg/mL used for?

Recognizes a protein of 52 kDa-58 kDa, identified as CD46 (also known as membrane cofactor protein, MCP) . CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial ti

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

You Might Also Like
Mucin 5AC (MUC5AC) (58M1), CF405S conjugate, 0.1mg/mL
Mucin 5AC (MUC5AC) (58M1), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC041003-500
CD11c (HC1/1), CF680R conjugate, 0.1mg/mL
CD11c (HC1/1), CF680R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC810152-500
CD47 (B6H12.2), CF568 conjugate, 0.1mg/mL
CD47 (B6H12.2), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680437-100
HSP27 (G3.1), CF647 conjugate, 0.1mg/mL
HSP27 (G3.1), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470861-100
CD45RO (190-2F2.5), CF405S conjugate, 0.1mg/mL
CD45RO (190-2F2.5), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC041081-500
Major Vault Protein (MVP) (1032), CF488A conjugate, 0.1mg/mL
Major Vault Protein (MVP) (1032), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880225-100
Cytochrome C (CTC05), CF740 conjugate, 0.1mg/mL
Cytochrome C (CTC05), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740887-500
CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF405S conjugate, 0.1mg/mL
CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC041779-500