CD46 (197-2B1), CF405S conjugate, 0.1mg/mL

Catalog number BNC040931-500

Price for BNC040931-500

Size / count 1x 500 µL

About this product

Recognizes a protein of 52 kDa-58 kDa, identified as CD46 (also known as membrane cofactor protein, MCP) . CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria. This MAb can be applied to test complement activation in pseudo-allergic reactions to acetylsalicylic acid and to test for measles virus infection of cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC040931-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: AHUS2; Complement membrane cofactor protein; MCP; Measles virus receptor; Membrane cofactor protein; MIC10; TLX; Trophoblast leucocyte common antigen; Trophoblast lymphocyte cross reactive antigen
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD46
Gene ID: 4179
NCBI Gene ID: 510402
UniProt: P15529
Swiss Prot: P15529
Host: Mouse
Species Reactivity: Human
Reactivity: CD46
Immunogen: Stimulated human leukocytes
Target Antigen: CD46
Clonality: Monoclonal
Clone: 197-2B1
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, surface (published) |Functional studies (published)
Field of Research: Immunology
Positive Control: K562, U937, HL60, HeLa and Jurkat cells, and human lymphocytes. Lymph node and tonsil.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 52-58 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for CD46 (197-2B1), CF405S conjugate, 0.1mg/mL?

The catalog number for CD46 (197-2B1), CF405S conjugate, 0.1mg/mL is BNC040931-500.

What sizes are available for CD46 (197-2B1), CF405S conjugate, 0.1mg/mL?

CD46 (197-2B1), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD46 (197-2B1), CF405S conjugate, 0.1mg/mL in stock?

CD46 (197-2B1), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD46 (197-2B1), CF405S conjugate, 0.1mg/mL?

CD46 (197-2B1), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD46 (197-2B1), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for CD46 (197-2B1), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD46 (197-2B1), CF405S conjugate, 0.1mg/mL?

The safety data sheet for CD46 (197-2B1), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102af7/msds/bnc040931-500.pdf.

What is CD46 (197-2B1), CF405S conjugate, 0.1mg/mL used for?

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.