CD46 (197-2B1), CF647 conjugate, 0.1mg/mL

Catalog number BNC470931-100

Price for BNC470931-100

Size / count 1x 100 µL

About this product

Recognizes a protein of 52 kDa-58 kDa, identified as CD46 (also known as membrane cofactor protein, MCP) . CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria. This MAb can be applied to test complement activation in pseudo-allergic reactions to acetylsalicylic acid and to test for measles virus infection of cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC470931-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: AHUS2; Complement membrane cofactor protein; MCP; Measles virus receptor; Membrane cofactor protein; MIC10; TLX; Trophoblast leucocyte common antigen; Trophoblast lymphocyte cross reactive antigen
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD46
Gene ID: 4179
NCBI Gene ID: 510402
UniProt: P15529
Swiss Prot: P15529
Host: Mouse
Species Reactivity: Human
Reactivity: CD46
Immunogen: Stimulated human leukocytes
Target Antigen: CD46
Clonality: Monoclonal
Clone: 197-2B1
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, surface (published) |Functional studies (published)
Field of Research: Immunology
Positive Control: K562, U937, HL60, HeLa and Jurkat cells, and human lymphocytes. Lymph node and tonsil.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 52-58 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for CD46 (197-2B1), CF647 conjugate, 0.1mg/mL?

The catalog number for CD46 (197-2B1), CF647 conjugate, 0.1mg/mL is BNC470931-100.

What sizes are available for CD46 (197-2B1), CF647 conjugate, 0.1mg/mL?

CD46 (197-2B1), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD46 (197-2B1), CF647 conjugate, 0.1mg/mL in stock?

CD46 (197-2B1), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD46 (197-2B1), CF647 conjugate, 0.1mg/mL?

CD46 (197-2B1), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD46 (197-2B1), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for CD46 (197-2B1), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD46 (197-2B1), CF647 conjugate, 0.1mg/mL?

The safety data sheet for CD46 (197-2B1), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a3061270361e104c13/msds/bnc470931-100.pdf.

What is CD46 (197-2B1), CF647 conjugate, 0.1mg/mL used for?

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.