CD47 (B6H12.2), Biotin conjugate, 0.1mg/mL — image 1 of 3

Product details

CD47 (B6H12.2), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0437-100

Price for BNCB0437-100

Size / count 1x 100 µL

About this product

This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB0437-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Antigenic Surface Determinant Protein OA3; IAP; Integrin Associated Protein; Integrin Associated Signal Transducer; MER6; OA3; Protein MER6; Rh Related Antigen
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD47
Gene ID: 961
NCBI Gene ID: 446414
UniProt: Q08722
Swiss Prot: Q08722
Host: Mouse
Species Reactivity: Human, Mouse
Reactivity: CD47
Immunogen: Intact CD47 purified from placenta
Target Antigen: CD47
Clonality: Monoclonal
Clone: B6H12.2
Type: Primary
Source: Animal
Origin: Animal
Applications: IF (published) |Flow, surface (verified) |Functional studies (published) |IF (verified) |IP (published) |WB (published)
Field of Research: Cell adhesion, Hematology, Neuroscience, Signal transduction
Positive Control: HUVEC, OVCA3 cells, Placenta, Brain and Ovarian Tumors|MCF-7
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: ~50 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications._x000D_ 1. J Biol Chem (2002) 277(12): 10028-10036. (functional studies)_x000D_ 2. Cell (2009) 138(2): 286-299. (functional studies)_x000D_ 3. J Immunol (2014) 193: 3914-3924. (immunofluorescence)_x000D_ 4. J Immunol (2015) 195: 661-671. (flow, surface; immunofluorescence; western)_x000D_ 5. Nat Med (2019) 25(4): 612-619. (immunoprecipitation)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for CD47 (B6H12.2), Biotin conjugate, 0.1mg/mL?

The catalog number for CD47 (B6H12.2), Biotin conjugate, 0.1mg/mL is BNCB0437-100.

What sizes are available for CD47 (B6H12.2), Biotin conjugate, 0.1mg/mL?

CD47 (B6H12.2), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD47 (B6H12.2), Biotin conjugate, 0.1mg/mL in stock?

CD47 (B6H12.2), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD47 (B6H12.2), Biotin conjugate, 0.1mg/mL?

CD47 (B6H12.2), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD47 (B6H12.2), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for CD47 (B6H12.2), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD47 (B6H12.2), Biotin conjugate, 0.1mg/mL?

The safety data sheet for CD47 (B6H12.2), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD47 (B6H12.2), Biotin conjugate, 0.1mg/mL used for?

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.