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Product details

CD47 (B6H12.2), CF594 conjugate, 0.1mg/mL

Catalog number BNC940437-500

Price for BNC940437-500

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Size / count 1x 500 µL

About this product

This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC940437-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Antigenic Surface Determinant Protein OA3; IAP; Integrin Associated Protein; Integrin Associated Signal Transducer; MER6; OA3; Protein MER6; Rh Related Antigen
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD47
Gene ID
961
NCBI Gene ID
446414
UniProt
Q08722
Swiss Prot
Q08722
Host
Mouse
Species Reactivity
Human, Mouse
Reactivity
CD47
Immunogen
Intact CD47 purified from placenta
Target Antigen
CD47
Clonality
Monoclonal
Clone
B6H12.2
Type
Primary
Source
Animal
Origin
Animal
Applications
IF (published) |Flow, surface (verified) |Functional studies (published) |IF (verified) |IP (published) |WB (published)
Field of Research
Cell adhesion, Hematology, Neuroscience, Signal transduction
Positive Control
HUVEC, OVCA3 cells, Placenta, Brain and Ovarian Tumors|MCF-7
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~50 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications._x000D_ 1. J Biol Chem (2002) 277(12): 10028-10036. (functional studies)_x000D_ 2. Cell (2009) 138(2): 286-299. (functional studies)_x000D_ 3. J Immunol (2014) 193: 3914-3924. (immunofluorescence)_x000D_ 4. J Immunol (2015) 195: 661-671. (flow, surface; immunofluorescence; western)_x000D_ 5. Nat Med (2019) 25(4): 612-619. (immunoprecipitation)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for CD47 (B6H12.2), CF594 conjugate, 0.1mg/mL?

The catalog number for CD47 (B6H12.2), CF594 conjugate, 0.1mg/mL is BNC940437-500.

What sizes are available for CD47 (B6H12.2), CF594 conjugate, 0.1mg/mL?

CD47 (B6H12.2), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD47 (B6H12.2), CF594 conjugate, 0.1mg/mL in stock?

CD47 (B6H12.2), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD47 (B6H12.2), CF594 conjugate, 0.1mg/mL?

CD47 (B6H12.2), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD47 (B6H12.2), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for CD47 (B6H12.2), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD47 (B6H12.2), CF594 conjugate, 0.1mg/mL?

The safety data sheet for CD47 (B6H12.2), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD47 (B6H12.2), CF594 conjugate, 0.1mg/mL used for?

This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

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