CD54 (W-CAM-1; same as Wehi-CAM-1 or 1H4), CF647 conjugate, 0.1mg/mL

Catalog number BNC470988-500

Price for BNC470988-500

Size / count 1x 500 µL

About this product

Recognizes an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1) (Workshop IV) . It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1) . This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. W-CAM-1 MAb blocks aggregation of cell lines mediated by the ICAM-1 and blocks homotypic binding of purified populations of activated T- and B-lymphocytes and also aggregation of mixed T- and B-cell blasts. It inhibits T-cell adhesion to normal human endothelial cells. Activation induced by cell-cell contact (mixed lymphocyte reaction, T-cell mediated B-cell activation) is significantly inhibited. This MAb blocks elements of both effector arms of immune system (cytotoxic cell function and Ig production) .Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC470988-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Intestinal mucin-3A; intestinal mucin-like; MUC3; MUC3A; MUC3B; mucin 3, intestinal; mucin 3A, cell surface associated; mucin 3A, intestinal; mucin 3B, cell surface associated
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ICAM1
Gene ID: 3383
NCBI Gene ID: 643447
UniProt: P05362
Swiss Prot: P05362
Host: Mouse
Species Reactivity: Human
Reactivity: CD54
Immunogen: Raji Burkitt lymphoma cells
Target Antigen: CD54
Clonality: Monoclonal
Clone: W-CAM-1; same as Wehi-CAM-1 or 1H4
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Immunology
Positive Control: Raji cells, MOLT 4, HeLa or SW480 cells. Human tonsil.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 85-115 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for CD54 (W-CAM-1; same as Wehi-CAM-1 or 1H4), CF647 conjugate, 0.1mg/mL?

The catalog number for CD54 (W-CAM-1; same as Wehi-CAM-1 or 1H4), CF647 conjugate, 0.1mg/mL is BNC470988-500.

What sizes are available for CD54 (W-CAM-1; same as Wehi-CAM-1 or 1H4), CF647 conjugate, 0.1mg/mL?

CD54 (W-CAM-1; same as Wehi-CAM-1 or 1H4), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD54 (W-CAM-1; same as Wehi-CAM-1 or 1H4), CF647 conjugate, 0.1mg/mL in stock?

CD54 (W-CAM-1; same as Wehi-CAM-1 or 1H4), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD54 (W-CAM-1; same as Wehi-CAM-1 or 1H4), CF647 conjugate, 0.1mg/mL?

CD54 (W-CAM-1; same as Wehi-CAM-1 or 1H4), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD54 (W-CAM-1; same as Wehi-CAM-1 or 1H4), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for CD54 (W-CAM-1; same as Wehi-CAM-1 or 1H4), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD54 (W-CAM-1; same as Wehi-CAM-1 or 1H4), CF647 conjugate, 0.1mg/mL?

The safety data sheet for CD54 (W-CAM-1; same as Wehi-CAM-1 or 1H4), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a9061270361e106f15/msds/bnc470988-500.pdf.

What is CD54 (W-CAM-1; same as Wehi-CAM-1 or 1H4), CF647 conjugate, 0.1mg/mL used for?

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.