Product details
Catalog number BNC742271-100
Price for BNC742271-100
Size / count 1x 100 µL
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD) . Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. MBD1 has also been predicted to be involved in the development and progression of tumors, and it has been shown that MBD1 is significantly upregulated in pancreatic cancer tissues when compared with surrounding normal tissues. Furthermore, MBD1 may serve as a potential therapeutic target for pancreatic cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF740 conjugate, 0.1mg/mL is BNC742271-100.
MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a3061270361e104fba/msds/bnc742271-100.pdf.
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD) . Each of these proteins,
Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.
Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.
Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.