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Product details

MTAP (Tumor Suppressor Marker) (MTAP/1813), CF740 conjugate, 0.1mg/mL

Catalog number BNC741813-500

Price for BNC741813-500

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Size / count 1x 500 µL

About this product

This antibody recognizes a protein of 31 kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase) . It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked to the tumor suppressor gene, p16INK4A. Deficient levels of MTAP can occur in cancers primarily through co-deletion of the MTAP gene and the p16INK4A gene. Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e.g. antifolates), whose mechanism of action, in part, involves this de novo purine pathway.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC741813-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
BDMF; DMSFH; DMSMFH; Epididymis luminal protein 249; HEL249; LGMBF; MeSAdo phosphorylase; Methylthioadenosine phosphorylase; MSAP; MTA phosphorylase; MTAP; MTAPase; S-methyl-5''-thioadenosine phosphorylase
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MTAP
Gene ID
4507
NCBI Gene ID
193268
UniProt
Q13126
Swiss Prot
Q13126
Host
Mouse
Species Reactivity
Human
Reactivity
MTAP
Immunogen
Recombinant human MTAP protein fragment (aa97-196) (exact sequence is proprietary)
Target Antigen
MTAP
Clonality
Monoclonal
Clone
MTAP/1813
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
DNA repair
Positive Control
HepG2, A431, HeLa, HAP1 or MCF-7 cells. Kidney.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
31 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), Bos taurus (bovine)
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF740 conjugate, 0.1mg/mL?

The catalog number for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF740 conjugate, 0.1mg/mL is BNC741813-500.

What sizes are available for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF740 conjugate, 0.1mg/mL?

MTAP (Tumor Suppressor Marker) (MTAP/1813), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MTAP (Tumor Suppressor Marker) (MTAP/1813), CF740 conjugate, 0.1mg/mL in stock?

MTAP (Tumor Suppressor Marker) (MTAP/1813), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MTAP (Tumor Suppressor Marker) (MTAP/1813), CF740 conjugate, 0.1mg/mL?

MTAP (Tumor Suppressor Marker) (MTAP/1813), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF740 conjugate, 0.1mg/mL?

The safety data sheet for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e10063f/msds/bnc741813-500.pdf.

What is MTAP (Tumor Suppressor Marker) (MTAP/1813), CF740 conjugate, 0.1mg/mL used for?

This antibody recognizes a protein of 31 kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase) . It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding M

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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