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Product details

CD7 (T3-3A1), 1mg/mL

Catalog number BNUM0978-50

Price for BNUM0978-50

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Size / count 1x 50 µL

About this product

Recognizes a protein of 40 kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM0978-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD27 ligand (CD27L) ; CD27LG; Ki24; Surface antigen CD70; Tumor necrosis factor (ligand) superfamily, member 7 (TNFSF7)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD7
Gene ID
924
NCBI Gene ID
186820
UniProt
P09564
Swiss Prot
P09564
Host
Mouse
Species Reactivity
Human
Reactivity
CD7
Immunogen
Human T cells
Target Antigen
CD7
Clonality
Monoclonal
Clone
T3-3A1
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |Functional studies (published) |IF (published) |ELISA (published) |IP (published)
Field of Research
Immunology, Signal transduction
Positive Control
Jurkat, HUT-78, Molt-4, CEM cells, or human peripheral blood lymphocytes. Lymph node and tonsil.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
40 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. PNAS USA (1979) 76: 5829-5833. PNAS USA (1980) 77(5): 2914-2918. (IP; functional studies) J Immunol Meth (1987) 96(2), 201-209. (cell ELISA) PNAS USA (1996) 93: 10348-10353. (cell depletion)>/li> Blood (1998) 91(8) 2760-2771. (Flow) J Cell Biol (1998) 142(5): 1245-1256. (IF; IP) Theranostics (2018) 8(21): 6070-6087. (mAb characterization; in vivo imaging)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for CD7 (T3-3A1), 1mg/mL?

The catalog number for CD7 (T3-3A1), 1mg/mL is BNUM0978-50.

What sizes are available for CD7 (T3-3A1), 1mg/mL?

CD7 (T3-3A1), 1mg/mL is available in the following size(s): 1x 50 µL.

Is CD7 (T3-3A1), 1mg/mL in stock?

CD7 (T3-3A1), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD7 (T3-3A1), 1mg/mL?

CD7 (T3-3A1), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD7 (T3-3A1), 1mg/mL?

Estimated delivery time for CD7 (T3-3A1), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD7 (T3-3A1), 1mg/mL?

The safety data sheet for CD7 (T3-3A1), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD7 (T3-3A1), 1mg/mL used for?

Recognizes a protein of 40 kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk fro

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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