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Product details
Catalog number BNUB0749-100
Price for BNUB0749-100
Size / count 1x 100 µL
CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 β chain (CD8 α /β ) or as a homodimer (CD8 α /α ) . A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4 /CD8-. Anaplastic large cell lymphoma is usually CD4 and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for CD8 (C8/144B), 0.2mg/mL is BNUB0749-100.
CD8 (C8/144B), 0.2mg/mL is available in the following size(s): 1x 100 µL.
CD8 (C8/144B), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
CD8 (C8/144B), 0.2mg/mL is manufactured by Biotium.
Estimated delivery time for CD8 (C8/144B), 0.2mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for CD8 (C8/144B), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 β chain (CD8 α /β ) or as a homodimer (CD8 α /α ) . A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association
Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.
Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.
We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.
