CD8 (C8/144B), CF647 conjugate, 0.1mg/mL

Catalog number BNC470749-500

Price for BNC470749-500

Size / count 1x 500 µL

About this product

CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 β chain (CD8 α /β ) or as a homodimer (CD8 α /α ) . A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4 /CD8-. Anaplastic large cell lymphoma is usually CD4 and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC470749-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD8 antigen, alpha polypeptide (p32), T8/Leu-2 T-lymphocyte differentiation antigen, Ly3, LYT3, MAL, T-cell surface glycoprotein CD8 alpha chain
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD8A
Gene ID: 925
NCBI Gene ID: 85258
UniProt: P01732
Swiss Prot: P01732
Host: Mouse
Species Reactivity: Human
Reactivity: CD8
Immunogen: A 13 amino acid peptide from C-terminal cytoplasmic domain of alpha chain of human CD8 molecule.
Target Antigen: CD8
Clonality: Monoclonal
Clone: C8/144B
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Immunology
Positive Control: HuT78 or hPBL. Tonsil
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 32 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for CD8 (C8/144B), CF647 conjugate, 0.1mg/mL?

The catalog number for CD8 (C8/144B), CF647 conjugate, 0.1mg/mL is BNC470749-500.

What sizes are available for CD8 (C8/144B), CF647 conjugate, 0.1mg/mL?

CD8 (C8/144B), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD8 (C8/144B), CF647 conjugate, 0.1mg/mL in stock?

CD8 (C8/144B), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD8 (C8/144B), CF647 conjugate, 0.1mg/mL?

CD8 (C8/144B), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD8 (C8/144B), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for CD8 (C8/144B), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD8 (C8/144B), CF647 conjugate, 0.1mg/mL?

The safety data sheet for CD8 (C8/144B), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b2061270361e10a24f/msds/bnc470749-500.pdf.

What is CD8 (C8/144B), CF647 conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.