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Product details

CD8 (C8/468), 0.2mg/mL

Catalog number BNUB0468-100

Price for BNUB0468-100

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Size / count 1x 100 µL

About this product

CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 β chain (CD8 α /β ) or as a homodimer (CD8 α /α ) . A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4 /CD8-. Anaplastic large cell lymphoma is usually CD4 and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB0468-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD8 antigen, alpha polypeptide (p32), T8/Leu-2 T-lymphocyte differentiation antigen, Ly3, LYT3, MAL, T-cell surface glycoprotein CD8 alpha chain
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD8A
Gene ID
925
NCBI Gene ID
85258
UniProt
P01732
Swiss Prot
P01732
Host
Mouse
Species Reactivity
Human
Reactivity
CD8
Immunogen
Human CD8 recombinant protein
Target Antigen
CD8
Clonality
Monoclonal
Clone
C8/468
Type
Primary
Source
Animal
Origin
Animal
Applications
IF (verified) |IHC, FFPE (verified)
Field of Research
Immunology
Positive Control
HuT78 or hPBL. Tonsil
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
32 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for CD8 (C8/468), 0.2mg/mL?

The catalog number for CD8 (C8/468), 0.2mg/mL is BNUB0468-100.

What sizes are available for CD8 (C8/468), 0.2mg/mL?

CD8 (C8/468), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is CD8 (C8/468), 0.2mg/mL in stock?

CD8 (C8/468), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD8 (C8/468), 0.2mg/mL?

CD8 (C8/468), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD8 (C8/468), 0.2mg/mL?

Estimated delivery time for CD8 (C8/468), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD8 (C8/468), 0.2mg/mL?

The safety data sheet for CD8 (C8/468), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD8 (C8/468), 0.2mg/mL used for?

CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 β chain (CD8 α /β ) or as a homodimer (CD8 α /α ) . A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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