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Product details

CD8 (RIV11), 1mg/mL

Catalog number BNUM0333-50

Price for BNUM0333-50

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Size / count 1x 50 µL

About this product

Recognizes a protein of 32 kDa, identified as CD8a (also known as CD8 chain, T cell co-receptor, Leu2, and T8) . CD8 molecule consists of two chains, termed and chain, which are expressed as a disulphide-linked heterodimer or as an homodimer. CD8 is expressed on T cell subset (cytotoxic/suppressor T cells), thymocytes and NK cells. The majority of CD8 T-cells expresses CD8 as heterodimer. Some subpopulation of CD8 T cells as well as NK cells may express homodimer. CD8 functions as a co-receptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 chain (but not chain) . The cytoplasmic domain of CD8 associates with p56lck tyrosine kinase. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM0333-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD8 antigen, alpha polypeptide (p32), T8/Leu-2 T-lymphocyte differentiation antigen, Ly3, LYT3, MAL, T-cell surface glycoprotein CD8 alpha chain
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD8A
Gene ID
925
NCBI Gene ID
85258
UniProt
P01732
Swiss Prot
P01732
Host
Mouse
Species Reactivity
Human
Reactivity
CD8
Immunogen
Human peripheral lymphocytes
Target Antigen
CD8
Clonality
Monoclonal
Clone
RIV11
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (verified) |IF (verified)
Field of Research
Immunology
Positive Control
HuT78 or hPBL. Tonsil
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
32 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. Knapp W. et. al. Leukocyte Typing IV, p342-343, Oxford University Press, 1989.
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for CD8 (RIV11), 1mg/mL?

The catalog number for CD8 (RIV11), 1mg/mL is BNUM0333-50.

What sizes are available for CD8 (RIV11), 1mg/mL?

CD8 (RIV11), 1mg/mL is available in the following size(s): 1x 50 µL.

Is CD8 (RIV11), 1mg/mL in stock?

CD8 (RIV11), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD8 (RIV11), 1mg/mL?

CD8 (RIV11), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD8 (RIV11), 1mg/mL?

Estimated delivery time for CD8 (RIV11), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD8 (RIV11), 1mg/mL?

The safety data sheet for CD8 (RIV11), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD8 (RIV11), 1mg/mL used for?

Recognizes a protein of 32 kDa, identified as CD8a (also known as CD8 chain, T cell co-receptor, Leu2, and T8) . CD8 molecule consists of two chains, termed and chain, which are expressed as a disulphide-linked heterodimer or as an homodimer. CD8 is expressed on T cell subset (cytotoxic/suppressor T

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

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