Cyclin B1 (CCNB1/1098), CF640R conjugate, 0.1mg/mL — image 1 of 9

Product details

Cyclin B1 (CCNB1/1098), CF640R conjugate, 0.1mg/mL

Catalog number BNC401098-500

Price for BNC401098-500

Size / count 1x 500 µL

About this product

This antibody recognizes a protein of 55-62 kDa, identified as cyclin B1. In mammals, cyclin B associates with inactive p34cdc2, which facilitates phosphorylation of p34cdc2 at aa 14Thr and 15Tyr. This maintains the inactive state until the end of G2-phase. The inactive cyclin B-p34cdc2 complex continues to accumulate in the cytoplasm until the completion of DNA synthesis, when Cdc25, a specific protein phosphatase, dephosphorylates aa 14Thr and 15Tyr of p34cdc2 rendering the complex active at the G2/M boundary. This mitotic kinase complex remains active until the metaphase/anaphase transition when cyclin B is degraded. This degradation process is ubiquitin-dependent and is necessary for the cell to exit mitosis. So, cyclin B-p34cdc2 plays a critical role in G2 to M transition. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC401098-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CCNB, CCNB1, CCNB1_HUMAN, G2 Mitotic Specific Cyclin B1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CCNB1
Gene ID: 891
NCBI Gene ID: 23960
UniProt: P14635
Swiss Prot: P14635
Host: Mouse
Species Reactivity: Human, Mouse
Reactivity: Cyclin B1
Immunogen: Recombinant human full-length CCNB1 protein
Target Antigen: Cyclin B1
Clonality: Monoclonal
Clone: CCNB1/1098
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow (verified) |IF (verified) |IHC, FFPE (verified)
Field of Research: Cell cycle
Positive Control: Cell line in logarithmic growth phase. Tonsil or testicular, endometrial, prostate or ovarian carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 55-62 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for Cyclin B1 (CCNB1/1098), CF640R conjugate, 0.1mg/mL?

The catalog number for Cyclin B1 (CCNB1/1098), CF640R conjugate, 0.1mg/mL is BNC401098-500.

What sizes are available for Cyclin B1 (CCNB1/1098), CF640R conjugate, 0.1mg/mL?

Cyclin B1 (CCNB1/1098), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cyclin B1 (CCNB1/1098), CF640R conjugate, 0.1mg/mL in stock?

Cyclin B1 (CCNB1/1098), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cyclin B1 (CCNB1/1098), CF640R conjugate, 0.1mg/mL?

Cyclin B1 (CCNB1/1098), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cyclin B1 (CCNB1/1098), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Cyclin B1 (CCNB1/1098), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cyclin B1 (CCNB1/1098), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Cyclin B1 (CCNB1/1098), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cyclin B1 (CCNB1/1098), CF640R conjugate, 0.1mg/mL used for?

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.