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Product details

Cytokeratin 10 (KRT10/844), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0844-100

Price for BNCB0844-100

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Size / count 1x 100 µL

About this product

This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10) . CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB0844-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
BCIE, BIE, EHK, Keratin Type I Cytoskeletal 10, KRT10
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT10
Gene ID
3858
NCBI Gene ID
99936
UniProt
P13645
Swiss Prot
P13645
Host
Mouse
Species Reactivity
Human, Mouse
Reactivity
Cytokeratin 10
Immunogen
Recombinant human KRT10 protein
Target Antigen
Cytokeratin 10
Clonality
Monoclonal
Clone
KRT10/844
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Cytoskeleton
Positive Control
A431, HeLa, MCF7 cells. Esophagus or tonsil.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
56.5 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Cytokeratin 10 (KRT10/844), Biotin conjugate, 0.1mg/mL?

The catalog number for Cytokeratin 10 (KRT10/844), Biotin conjugate, 0.1mg/mL is BNCB0844-100.

What sizes are available for Cytokeratin 10 (KRT10/844), Biotin conjugate, 0.1mg/mL?

Cytokeratin 10 (KRT10/844), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Cytokeratin 10 (KRT10/844), Biotin conjugate, 0.1mg/mL in stock?

Cytokeratin 10 (KRT10/844), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin 10 (KRT10/844), Biotin conjugate, 0.1mg/mL?

Cytokeratin 10 (KRT10/844), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin 10 (KRT10/844), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin 10 (KRT10/844), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin 10 (KRT10/844), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin 10 (KRT10/844), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cytokeratin 10 (KRT10/844), Biotin conjugate, 0.1mg/mL used for?

This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10) . CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

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