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Product details

Cytokeratin 10 (KRT10/844), CF594 conjugate, 0.1mg/mL

Catalog number BNC940844-100

Price for BNC940844-100

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Size / count 1x 100 µL

About this product

This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10) . CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC940844-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
BCIE, BIE, EHK, Keratin Type I Cytoskeletal 10, KRT10
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT10
Gene ID
3858
NCBI Gene ID
99936
UniProt
P13645
Swiss Prot
P13645
Host
Mouse
Species Reactivity
Human, Mouse
Reactivity
Cytokeratin 10
Immunogen
Recombinant human KRT10 protein
Target Antigen
Cytokeratin 10
Clonality
Monoclonal
Clone
KRT10/844
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Cytoskeleton
Positive Control
A431, HeLa, MCF7 cells. Esophagus or tonsil.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
56.5 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for Cytokeratin 10 (KRT10/844), CF594 conjugate, 0.1mg/mL?

The catalog number for Cytokeratin 10 (KRT10/844), CF594 conjugate, 0.1mg/mL is BNC940844-100.

What sizes are available for Cytokeratin 10 (KRT10/844), CF594 conjugate, 0.1mg/mL?

Cytokeratin 10 (KRT10/844), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Cytokeratin 10 (KRT10/844), CF594 conjugate, 0.1mg/mL in stock?

Cytokeratin 10 (KRT10/844), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin 10 (KRT10/844), CF594 conjugate, 0.1mg/mL?

Cytokeratin 10 (KRT10/844), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin 10 (KRT10/844), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin 10 (KRT10/844), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin 10 (KRT10/844), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin 10 (KRT10/844), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cytokeratin 10 (KRT10/844), CF594 conjugate, 0.1mg/mL used for?

This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10) . CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

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