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Product details

Cytokeratin 6 (LHK6), CF640R conjugate, 0.1mg/mL

Catalog number BNC400675-500

Price for BNC400675-500

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Size / count 1x 500 µL

About this product

This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6 (CK6) . In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and Cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human Cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies. Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins) . Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC400675-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CK6A, CK6B, CK6C, CK6D, CK6E, Keratin Type II Cytoskeletal 6A, Keratin Type II Cytoskeletal 6B, Keratin Type II Cytoskeletal 6C, Keratin Type II Cytoskeletal 6D, Keratin Type II Cytoskeletal 6E, KRT6, KRT6A, KRT6B, KRT6C, KRT6D, KRT6E
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT6A; KRT6B; KRT6C
Gene ID
3853-KRT6A, 3854-KRT6B, 286887-KRT6C
NCBI Gene ID
700779
UniProt
P02538-KRT6A, P04259-KRT6B, P48668-KRT6C
Swiss Prot
P02538-KRT6A, P04259-KRT6B, P48668-KRT6C
Host
Mouse
Species Reactivity
Human, Mouse
Reactivity
Cytokeratin 6
Immunogen
A synthetic peptide of 11 amino acids (GSSTIKYTTTS) from C-terminus of human keratin 6
Target Antigen
Cytokeratin 6
Clonality
Monoclonal
Clone
LHK6
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Cytoskeleton
Positive Control
Tonsil or basal cell carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
56 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for Cytokeratin 6 (LHK6), CF640R conjugate, 0.1mg/mL?

The catalog number for Cytokeratin 6 (LHK6), CF640R conjugate, 0.1mg/mL is BNC400675-500.

What sizes are available for Cytokeratin 6 (LHK6), CF640R conjugate, 0.1mg/mL?

Cytokeratin 6 (LHK6), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cytokeratin 6 (LHK6), CF640R conjugate, 0.1mg/mL in stock?

Cytokeratin 6 (LHK6), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin 6 (LHK6), CF640R conjugate, 0.1mg/mL?

Cytokeratin 6 (LHK6), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin 6 (LHK6), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin 6 (LHK6), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin 6 (LHK6), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin 6 (LHK6), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cytokeratin 6 (LHK6), CF640R conjugate, 0.1mg/mL used for?

This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6 (CK6) . In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and Cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding hu

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

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