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Product details

Cytokeratin 8 (C-43), CF568 conjugate, 0.1mg/mL

Catalog number BNC680688-100

Price for BNC680688-100

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Size / count 1x 100 µL

About this product

Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18) . CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19) . Reportedly, anti-CK8 is useful for the differentiation of lobular (ring-like, perinuclear) from ductal (peripheral-predominant) carcinoma of the breast.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC680688-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CARD2; CK8; CYK8; CYKER; Cytokeratin Endo A; DreK8; EndoA; K2C8; K8; Keratin 8; Krt 2.8; KRT8; Type-II Keratin Kb8
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT8
Gene ID
3856
NCBI Gene ID
533782; 708445
UniProt
P05787
Swiss Prot
P05787
Host
Mouse
Species Reactivity
Cow, Human, Pig, Rabbit, Sheep
Reactivity
Cytokeratin 8
Immunogen
Cytoskeletal preparation from HeLa cells
Target Antigen
Cytokeratin 8
Clonality
Monoclonal
Clone
C-43
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified)
Field of Research
Cancer, Cytoskeleton
Positive Control
MCF-7 or A431 cells. Skin, Colon, lung or breast carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
52.5 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for Cytokeratin 8 (C-43), CF568 conjugate, 0.1mg/mL?

The catalog number for Cytokeratin 8 (C-43), CF568 conjugate, 0.1mg/mL is BNC680688-100.

What sizes are available for Cytokeratin 8 (C-43), CF568 conjugate, 0.1mg/mL?

Cytokeratin 8 (C-43), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Cytokeratin 8 (C-43), CF568 conjugate, 0.1mg/mL in stock?

Cytokeratin 8 (C-43), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin 8 (C-43), CF568 conjugate, 0.1mg/mL?

Cytokeratin 8 (C-43), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin 8 (C-43), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin 8 (C-43), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin 8 (C-43), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin 8 (C-43), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e1009c9/msds/bnc680688-100.pdf.

What is Cytokeratin 8 (C-43), CF568 conjugate, 0.1mg/mL used for?

Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18) . CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

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