Cytokeratin 8 (KRT8/899), 0.2mg/mL

Catalog number BNUB0899-500

Price for BNUB0899-500

Size / count 1x 500 µL

About this product

Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18) . CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19) . Reportedly, anti-CK8 is useful for the differentiation of lobular (ring-like, perinuclear) from ductal (peripheral-predominant) carcinoma of the breast.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.

Specifications

Catalog number: BNUB0899-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CARD2; CK8; CYK8; CYKER; Cytokeratin Endo A; DreK8; EndoA; K2C8; K8; Keratin 8; Krt 2.8; KRT8; Type-II Keratin Kb8
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: KRT8
Gene ID: 3856
NCBI Gene ID: 533782; 708445
UniProt: P05787
Swiss Prot: P05787
Host: Mouse
Species Reactivity: Human, Monkey, Rabbit
Reactivity: Cytokeratin 8
Immunogen: Recombinant human KRT8 protein
Target Antigen: Cytokeratin 8
Clonality: Monoclonal
Clone: KRT8/899
Type: Primary
Source: Animal
Origin: Animal
Field of Research: Cancer, Cytoskeleton
Positive Control: MCF-7 or A431 cells. Skin, Colon, lung or breast carcinoma
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 52.5 kDa
References & Citations: Leube, R.E., et al. 1986. Cytokeratin expression in simple epithelia. III. Detection of mRNAs encoding human cytokeratins nos. 8 and 18 in normal and tumor cells by hybridization with cDNA sequences in vitro and in situ. Differentiation 33: 69-85. |
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgM, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for Cytokeratin 8 (KRT8/899), 0.2mg/mL?

The catalog number for Cytokeratin 8 (KRT8/899), 0.2mg/mL is BNUB0899-500.

What sizes are available for Cytokeratin 8 (KRT8/899), 0.2mg/mL?

Cytokeratin 8 (KRT8/899), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is Cytokeratin 8 (KRT8/899), 0.2mg/mL in stock?

Cytokeratin 8 (KRT8/899), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin 8 (KRT8/899), 0.2mg/mL?

Cytokeratin 8 (KRT8/899), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin 8 (KRT8/899), 0.2mg/mL?

Estimated delivery time for Cytokeratin 8 (KRT8/899), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin 8 (KRT8/899), 0.2mg/mL?

The safety data sheet for Cytokeratin 8 (KRT8/899), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cytokeratin 8 (KRT8/899), 0.2mg/mL used for?

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.