Cytokeratin 8 (KRT8/899), 1mg/mL

Catalog number BNUM0899-50

Price for BNUM0899-50

Size / count 1x 50 µL

About this product

Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18) . CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19) . Reportedly, anti-CK8 is useful for the differentiation of lobular (ring-like, perinuclear) from ductal (peripheral-predominant) carcinoma of the breast.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.

Specifications

Catalog number: BNUM0899-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CARD2; CK8; CYK8; CYKER; Cytokeratin Endo A; DreK8; EndoA; K2C8; K8; Keratin 8; Krt 2.8; KRT8; Type-II Keratin Kb8
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: KRT8
Gene ID: 3856
NCBI Gene ID: 533782; 708445
UniProt: P05787
Swiss Prot: P05787
Host: Mouse
Species Reactivity: Human, Monkey, Rabbit
Reactivity: Cytokeratin 8
Immunogen: Recombinant human KRT8 protein
Target Antigen: Cytokeratin 8
Clonality: Monoclonal
Clone: KRT8/899
Type: Primary
Source: Animal
Origin: Animal
Field of Research: Cancer, Cytoskeleton
Positive Control: MCF-7 or A431 cells. Skin, Colon, lung or breast carcinoma
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: 52.5 kDa
References & Citations: Leube, R.E., et al. 1986. Cytokeratin expression in simple epithelia. III. Detection of mRNAs encoding human cytokeratins nos. 8 and 18 in normal and tumor cells by hybridization with cDNA sequences in vitro and in situ. Differentiation 33: 69-85. |
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgM, kappa
Species: Mus musculus (mouse)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Cytokeratin 8 (KRT8/899), 1mg/mL?

The catalog number for Cytokeratin 8 (KRT8/899), 1mg/mL is BNUM0899-50.

What sizes are available for Cytokeratin 8 (KRT8/899), 1mg/mL?

Cytokeratin 8 (KRT8/899), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Cytokeratin 8 (KRT8/899), 1mg/mL in stock?

Cytokeratin 8 (KRT8/899), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin 8 (KRT8/899), 1mg/mL?

Cytokeratin 8 (KRT8/899), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin 8 (KRT8/899), 1mg/mL?

Estimated delivery time for Cytokeratin 8 (KRT8/899), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin 8 (KRT8/899), 1mg/mL?

The safety data sheet for Cytokeratin 8 (KRT8/899), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029b061270361e101d14/msds/bnum0899-50.pdf.

What is Cytokeratin 8 (KRT8/899), 1mg/mL used for?

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.