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Product details

Cytokeratin 8/18 (KRT8/803 + KRT18/835), CF488A conjugate, 0.1mg/mL

Catalog number BNC880979-500

Price for BNC880979-500

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Size / count 1x 500 µL

About this product

Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18) . This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immuno-histochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC880979-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
P145; Steel Factor Receptor; Stem Cell Factor Receptor (SCF-Receptor) ; Mast Cell Growth Factor Receptor
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT8; KRT18
Gene ID
3856 (CK8); 3875 (CK18)
NCBI Gene ID
533782; 708445 (CK8); 406013 (CK18)
UniProt
P05787 (CK8); P05783 (CK18)
Swiss Prot
P05787 (CK8) ; P05783 (CK18)
Host
Mouse
Species Reactivity
Human
Reactivity
Cytokeratin 8/18
Immunogen
Recombinant full-length human KRT8 protein (KRT8/803) ; Recombinant full-length human KRT18 protein (KRT18/835)
Target Antigen
Cytokeratin 8/18
Clonality
Monoclonal
Clone
KRT8/803 KRT18/835
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Cytoskeleton
Positive Control
MCF-7 or A431 cells. Skin, Colon, lung or breast carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
52.5 kDa (CK8) ; 45 kDa (CK18)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG' s
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for Cytokeratin 8/18 (KRT8/803 + KRT18/835), CF488A conjugate, 0.1mg/mL?

The catalog number for Cytokeratin 8/18 (KRT8/803 + KRT18/835), CF488A conjugate, 0.1mg/mL is BNC880979-500.

What sizes are available for Cytokeratin 8/18 (KRT8/803 + KRT18/835), CF488A conjugate, 0.1mg/mL?

Cytokeratin 8/18 (KRT8/803 + KRT18/835), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cytokeratin 8/18 (KRT8/803 + KRT18/835), CF488A conjugate, 0.1mg/mL in stock?

Cytokeratin 8/18 (KRT8/803 + KRT18/835), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin 8/18 (KRT8/803 + KRT18/835), CF488A conjugate, 0.1mg/mL?

Cytokeratin 8/18 (KRT8/803 + KRT18/835), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin 8/18 (KRT8/803 + KRT18/835), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin 8/18 (KRT8/803 + KRT18/835), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin 8/18 (KRT8/803 + KRT18/835), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin 8/18 (KRT8/803 + KRT18/835), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cytokeratin 8/18 (KRT8/803 + KRT18/835), CF488A conjugate, 0.1mg/mL used for?

Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18) . This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tra

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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