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Product details

Cytokeratin, HMW (AE-3), CF594 conjugate, 0.1mg/mL

Catalog number BNC940257-100

Price for BNC940257-100

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Size / count 1x 100 µL

About this product

This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67 kDa (CK1) ; 64 kDa (CK3) ; 59 kDa (CK4) ; 58 kDa (CK5) ; 56 kDa (CK6) ; 52 kDa (CK8) . Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45, and 40 kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52 kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC940257-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
KRT2B; KRT2P; HUMCYT2A; Keratin, type II Cytoskeletal 2 oral; K76; Keratin 2p (K2P) ; Keratin-76; Cytokeratin-2P (CK-2P; Type-II Keratin Kb9
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT76
Gene ID
51350
NCBI Gene ID
654392
UniProt
Q01546
Swiss Prot
Q01546
Host
Mouse
Species Reactivity
Chicken, Cow, Dog, Human, Monkey, Mouse, Rabbit, Rat
Reactivity
Cytokeratin, HMW
Immunogen
Human epidermal keratin
Target Antigen
Cytokeratin, HMW
Clonality
Monoclonal
Clone
AE-3
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular|IF (published) |IHC, frozen (published) |IHC, FFPE (verified) |WB (published)
Field of Research
Cancer, Cytoskeleton
Positive Control
Epithelial cells, Skin or Adenocarcinomas
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
52-67 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. J Cell Biol (1982) 95: 580-588. (IHC, frozen; IF; WB)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for Cytokeratin, HMW (AE-3), CF594 conjugate, 0.1mg/mL?

The catalog number for Cytokeratin, HMW (AE-3), CF594 conjugate, 0.1mg/mL is BNC940257-100.

What sizes are available for Cytokeratin, HMW (AE-3), CF594 conjugate, 0.1mg/mL?

Cytokeratin, HMW (AE-3), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Cytokeratin, HMW (AE-3), CF594 conjugate, 0.1mg/mL in stock?

Cytokeratin, HMW (AE-3), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin, HMW (AE-3), CF594 conjugate, 0.1mg/mL?

Cytokeratin, HMW (AE-3), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin, HMW (AE-3), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin, HMW (AE-3), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin, HMW (AE-3), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin, HMW (AE-3), CF594 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e100710/msds/bnc940257-100.pdf.

What is Cytokeratin, HMW (AE-3), CF594 conjugate, 0.1mg/mL used for?

This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67 kDa (CK1) ; 64 kDa (CK3) ; 59 kDa (CK4) ; 58 kDa (CK5) ; 56 kDa (CK6) ; 52 kDa (CK8) . Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have mole

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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