Cytokeratin, LMW (AE-1), Biotin conjugate, 0.1mg/mL — image 1 of 2

Product details

Cytokeratin, LMW (AE-1), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0253-100

Price for BNCB0253-100

Size / count 1x 100 µL

About this product

This MAb recognizes the 56.5 kDa (CK10) ; 50 kDa (CK14) ; 50 kDa (CK15) ; 48 kDa (CK16) ; 40 kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40 kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52 kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB0253-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: K1B; KRT1B; Keratin, type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: KRT77
Gene ID: 374454
NCBI Gene ID: 334989
UniProt: Q7Z794
Swiss Prot: Q7Z794
Host: Mouse
Species Reactivity: Chicken, Cow, Dog, Human, Monkey, Mouse, Rabbit, Rat, Turtle
Reactivity: Cytokeratin, LMW
Immunogen: Human epidermal keratin
Target Antigen: Cytokeratin, LMW
Clonality: Monoclonal
Clone: AE-1
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (published) |IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer, Cytoskeleton
Positive Control: Skin, Squamous cell carcinoma (SCC)
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 40-56.5 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. Ann N Y Acad Sci (1986) 468: 302-15. (Flow)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for Cytokeratin, LMW (AE-1), Biotin conjugate, 0.1mg/mL?

The catalog number for Cytokeratin, LMW (AE-1), Biotin conjugate, 0.1mg/mL is BNCB0253-100.

What sizes are available for Cytokeratin, LMW (AE-1), Biotin conjugate, 0.1mg/mL?

Cytokeratin, LMW (AE-1), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Cytokeratin, LMW (AE-1), Biotin conjugate, 0.1mg/mL in stock?

Cytokeratin, LMW (AE-1), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin, LMW (AE-1), Biotin conjugate, 0.1mg/mL?

Cytokeratin, LMW (AE-1), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin, LMW (AE-1), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin, LMW (AE-1), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin, LMW (AE-1), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin, LMW (AE-1), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cytokeratin, LMW (AE-1), Biotin conjugate, 0.1mg/mL used for?

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.