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Product details

Cytokeratin, pan (Cocktail PAN-CK), CF405S conjugate, 0.1mg/mL

Catalog number BNC040999-100

Price for BNC040999-100

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Size / count 1x 100 µL

About this product

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67 kDa (CK1) ; 64 kDa (CK3) ; 59 kDa (CK4) ; 58 kDa (CK5) ; 56 kDa (CK6) ; 55 kDa (CK7) ; 52 kDa (CK8) ; 56.5 kDa (CK10) ; 53 kDa (CK13) ; 50 kDa (CK14) ; 50 kDa (CK15) ; 48 kDa (CK16) ; 46 kDa (CK17) ; 45 kDa (CK18) and 40 kDa (CK19) . Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRT-PAN is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It is useful in characterizing the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and shows high sensitivity in the recognition of epithelial cells and carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC040999-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
K1B; KRT1B; Keratin, type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT76, KRT77
Gene ID
374454 (KRT77) & 51350 (KRT76)
NCBI Gene ID
334989 (KRT77); 654392 (KRT76)
UniProt
Q7Z794 (KRT77); Q01546 (KRT76)
Swiss Prot
Q7Z794 (KRT77) & Q01546 (KRT76)
Host
Mouse
Species Reactivity
Chicken, Cow, Dog, Human, Monkey, Mouse, Rabbit, Rat
Reactivity
Cytokeratin, pan
Immunogen
Human epidermal keratin
Target Antigen
Cytokeratin, pan
Clonality
Monoclonal
Clone
Cocktail PAN-CK
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified)
Field of Research
Cancer, Cytoskeleton
Positive Control
Skin, Adeno- or Squamous carcinomas
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
40-67 kDa (Multiple)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG' s
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S

Frequently Asked Questions

What is the catalog number for Cytokeratin, pan (Cocktail PAN-CK), CF405S conjugate, 0.1mg/mL?

The catalog number for Cytokeratin, pan (Cocktail PAN-CK), CF405S conjugate, 0.1mg/mL is BNC040999-100.

What sizes are available for Cytokeratin, pan (Cocktail PAN-CK), CF405S conjugate, 0.1mg/mL?

Cytokeratin, pan (Cocktail PAN-CK), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Cytokeratin, pan (Cocktail PAN-CK), CF405S conjugate, 0.1mg/mL in stock?

Cytokeratin, pan (Cocktail PAN-CK), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin, pan (Cocktail PAN-CK), CF405S conjugate, 0.1mg/mL?

Cytokeratin, pan (Cocktail PAN-CK), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin, pan (Cocktail PAN-CK), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin, pan (Cocktail PAN-CK), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin, pan (Cocktail PAN-CK), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin, pan (Cocktail PAN-CK), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cytokeratin, pan (Cocktail PAN-CK), CF405S conjugate, 0.1mg/mL used for?

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67 kDa (CK1) ; 64 kDa (CK3) ; 59 kDa (CK4) ; 58 kDa (CK5) ; 56 kDa (CK6) ; 55 kDa (CK7)

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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