Cytokeratin, pan (Cocktail PAN-CK), CF543 conjugate, 0.1mg/mL — image 1 of 5

Product details

Cytokeratin, pan (Cocktail PAN-CK), CF543 conjugate, 0.1mg/mL

Catalog number BNC430999-100

Price for BNC430999-100

Size / count 1x 100 µL

About this product

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67 kDa (CK1) ; 64 kDa (CK3) ; 59 kDa (CK4) ; 58 kDa (CK5) ; 56 kDa (CK6) ; 55 kDa (CK7) ; 52 kDa (CK8) ; 56.5 kDa (CK10) ; 53 kDa (CK13) ; 50 kDa (CK14) ; 50 kDa (CK15) ; 48 kDa (CK16) ; 46 kDa (CK17) ; 45 kDa (CK18) and 40 kDa (CK19) . Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRT-PAN is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It is useful in characterizing the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and shows high sensitivity in the recognition of epithelial cells and carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC430999-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: K1B; KRT1B; Keratin, type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: KRT76, KRT77
Gene ID: 374454 (KRT77) & 51350 (KRT76)
NCBI Gene ID: 334989 (KRT77); 654392 (KRT76)
UniProt: Q7Z794 (KRT77); Q01546 (KRT76)
Swiss Prot: Q7Z794 (KRT77) & Q01546 (KRT76)
Host: Mouse
Species Reactivity: Chicken, Cow, Dog, Human, Monkey, Mouse, Rabbit, Rat
Reactivity: Cytokeratin, pan
Immunogen: Human epidermal keratin
Target Antigen: Cytokeratin, pan
Clonality: Monoclonal
Clone: Cocktail PAN-CK
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified)
Field of Research: Cancer, Cytoskeleton
Positive Control: Skin, Adeno- or Squamous carcinomas
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 40-67 kDa (Multiple)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG' s
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF543

Frequently Asked Questions

What is the catalog number for Cytokeratin, pan (Cocktail PAN-CK), CF543 conjugate, 0.1mg/mL?

The catalog number for Cytokeratin, pan (Cocktail PAN-CK), CF543 conjugate, 0.1mg/mL is BNC430999-100.

What sizes are available for Cytokeratin, pan (Cocktail PAN-CK), CF543 conjugate, 0.1mg/mL?

Cytokeratin, pan (Cocktail PAN-CK), CF543 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Cytokeratin, pan (Cocktail PAN-CK), CF543 conjugate, 0.1mg/mL in stock?

Cytokeratin, pan (Cocktail PAN-CK), CF543 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin, pan (Cocktail PAN-CK), CF543 conjugate, 0.1mg/mL?

Cytokeratin, pan (Cocktail PAN-CK), CF543 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin, pan (Cocktail PAN-CK), CF543 conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin, pan (Cocktail PAN-CK), CF543 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin, pan (Cocktail PAN-CK), CF543 conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin, pan (Cocktail PAN-CK), CF543 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a2061270361e1048e2/msds/bnc430999-100.pdf.

What is Cytokeratin, pan (Cocktail PAN-CK), CF543 conjugate, 0.1mg/mL used for?

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.