Cytokeratin, pan (Cocktail PAN-CK), CF594 conjugate, 0.1mg/mL — image 1 of 5

Product details

Cytokeratin, pan (Cocktail PAN-CK), CF594 conjugate, 0.1mg/mL

Catalog number BNC940999-500

Price for BNC940999-500

Size / count 1x 500 µL

About this product

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67 kDa (CK1) ; 64 kDa (CK3) ; 59 kDa (CK4) ; 58 kDa (CK5) ; 56 kDa (CK6) ; 55 kDa (CK7) ; 52 kDa (CK8) ; 56.5 kDa (CK10) ; 53 kDa (CK13) ; 50 kDa (CK14) ; 50 kDa (CK15) ; 48 kDa (CK16) ; 46 kDa (CK17) ; 45 kDa (CK18) and 40 kDa (CK19) . Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRT-PAN is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It is useful in characterizing the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and shows high sensitivity in the recognition of epithelial cells and carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC940999-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: K1B; KRT1B; Keratin, type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: KRT76, KRT77
Gene ID: 374454 (KRT77) & 51350 (KRT76)
NCBI Gene ID: 334989 (KRT77); 654392 (KRT76)
UniProt: Q7Z794 (KRT77); Q01546 (KRT76)
Swiss Prot: Q7Z794 (KRT77) & Q01546 (KRT76)
Host: Mouse
Species Reactivity: Chicken, Cow, Dog, Human, Monkey, Mouse, Rabbit, Rat
Reactivity: Cytokeratin, pan
Immunogen: Human epidermal keratin
Target Antigen: Cytokeratin, pan
Clonality: Monoclonal
Clone: Cocktail PAN-CK
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified)
Field of Research: Cancer, Cytoskeleton
Positive Control: Skin, Adeno- or Squamous carcinomas
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 40-67 kDa (Multiple)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG' s
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for Cytokeratin, pan (Cocktail PAN-CK), CF594 conjugate, 0.1mg/mL?

The catalog number for Cytokeratin, pan (Cocktail PAN-CK), CF594 conjugate, 0.1mg/mL is BNC940999-500.

What sizes are available for Cytokeratin, pan (Cocktail PAN-CK), CF594 conjugate, 0.1mg/mL?

Cytokeratin, pan (Cocktail PAN-CK), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cytokeratin, pan (Cocktail PAN-CK), CF594 conjugate, 0.1mg/mL in stock?

Cytokeratin, pan (Cocktail PAN-CK), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin, pan (Cocktail PAN-CK), CF594 conjugate, 0.1mg/mL?

Cytokeratin, pan (Cocktail PAN-CK), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin, pan (Cocktail PAN-CK), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin, pan (Cocktail PAN-CK), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin, pan (Cocktail PAN-CK), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin, pan (Cocktail PAN-CK), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cytokeratin, pan (Cocktail PAN-CK), CF594 conjugate, 0.1mg/mL used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.