• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

Cytokeratin, pan (AE-1 / AE-3), CF640R conjugate, 0.1mg/mL

Catalog number BNC400371-500

Price for BNC400371-500

Sign In for Pricing

Size / count 1x 500 µL

About this product

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include 67 kDa (CK1) ; 64 kDa (CK3) ; 59 kDa (CK4) ; 58 kDa (CK5) ; 56 kDa (CK6) ; 52 kDa (CK8) ; 56.5 kDa (CK10) ; 50 kDa (CK14) ; 50 kDa (CK15) ; 48 kDa (CK16) ; 40 kDa (CK19) . Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE-1/AE-3 is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC400371-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
K1B; KRT1B; Keratin, type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT76, KRT77
Gene ID
374454 (KRT77) & 51350 (KRT76)
NCBI Gene ID
334989 (KRT77); 654392 (KRT76)
UniProt
Q7Z794 (KRT77); Q01546 (KRT76)
Swiss Prot
Q7Z794 (KRT77) & Q01546 (KRT76)
Host
Mouse
Species Reactivity
Chicken, Cow, Dog, Human, Monkey, Mouse, Rabbit, Rat
Reactivity
Cytokeratin, pan
Immunogen
Human epidermal keratin
Target Antigen
Cytokeratin, pan
Clonality
Monoclonal
Clone
AE-1 / AE-3
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IHC, FFPE (verified)
Field of Research
Cancer, Cytoskeleton
Positive Control
Skin, Adeno- or Squamous carcinomas
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
40-67 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG' s
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for Cytokeratin, pan (AE-1 / AE-3), CF640R conjugate, 0.1mg/mL?

The catalog number for Cytokeratin, pan (AE-1 / AE-3), CF640R conjugate, 0.1mg/mL is BNC400371-500.

What sizes are available for Cytokeratin, pan (AE-1 / AE-3), CF640R conjugate, 0.1mg/mL?

Cytokeratin, pan (AE-1 / AE-3), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cytokeratin, pan (AE-1 / AE-3), CF640R conjugate, 0.1mg/mL in stock?

Cytokeratin, pan (AE-1 / AE-3), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin, pan (AE-1 / AE-3), CF640R conjugate, 0.1mg/mL?

Cytokeratin, pan (AE-1 / AE-3), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin, pan (AE-1 / AE-3), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin, pan (AE-1 / AE-3), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin, pan (AE-1 / AE-3), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin, pan (AE-1 / AE-3), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102783/msds/bnc400371-500.pdf.

What is Cytokeratin, pan (AE-1 / AE-3), CF640R conjugate, 0.1mg/mL used for?

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include 67 kDa (CK1) ; 64 kDa (CK3) ; 59 kDa (CK4) ; 58 kDa (CK5) ; 56 kDa (CK6) ; 52

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

You Might Also Like
Mucin 5AC (MUC5AC) (58M1), CF405S conjugate, 0.1mg/mL
Mucin 5AC (MUC5AC) (58M1), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC041003-500
CD11c (HC1/1), CF680R conjugate, 0.1mg/mL
CD11c (HC1/1), CF680R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC810152-500
CD47 (B6H12.2), CF568 conjugate, 0.1mg/mL
CD47 (B6H12.2), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680437-100
HSP27 (G3.1), CF647 conjugate, 0.1mg/mL
HSP27 (G3.1), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470861-100
CD45RO (190-2F2.5), CF405S conjugate, 0.1mg/mL
CD45RO (190-2F2.5), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC041081-500
Major Vault Protein (MVP) (1032), CF488A conjugate, 0.1mg/mL
Major Vault Protein (MVP) (1032), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880225-100
Cytochrome C (CTC05), CF740 conjugate, 0.1mg/mL
Cytochrome C (CTC05), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740887-500
CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF405S conjugate, 0.1mg/mL
CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC041779-500